Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using AI to screen for adrenal nodules on low-dose chest CT

Official title: The Application of Artificial Intelligence in Screening Adrenal Nodules in Low-dose Chest CT

Run by Peking University First Hospital · NCT07198152 · Data updated 2026-11-12

This project will try an AI tool to find adrenal nodules on routine low-dose chest CT scans for adults.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorPeking University First Hospital
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedSeptember 1, 2025
Main results expectedDecember 30, 2026
Study endsJanuary 30, 2027
Registry record updatedSeptember 30, 2025
Trial IDNCT07198152 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (over 18) who undergo routine low-dose chest CT scans with diagnostic-quality images and no history of malignant tumors.

Probably not a fit

People with prior malignant tumors or with CT images that are too poor in quality or have artifacts would likely not benefit from this screening tool.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect routine low-dose chest spiral CT images and extract imaging features from the adrenal gland regions to build a training dataset. They will use those features to train and validate an artificial intelligence algorithm for automatic detection and classification of adrenal nodules. The work is observational and uses existing clinical imaging without adding experimental interventions. Poor-quality images and patients with a history of malignancy will be excluded from the dataset.

Why it matters

Potential benefit: If successful, the AI tool could help detect adrenal nodules more quickly and consistently on routine chest CTs, supporting earlier follow-up and diagnosis.

How similar studies have gone: AI methods have shown promise for detecting incidental findings on CT generally, but AI specifically targeted to adrenal nodules on low-dose chest CT is relatively new and less well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The age of the population is over 18 years old, regardless of gender;
2. Images from chest low-dose CT plain scan during routine physical examination;

Exclusion Criteria:

1. Patients with a history of malignant tumors;
2. Imaging images with poor quality, artifacts, etc., which make analysis impossible.

Where it's running

  • Peking University First Hospital
    Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.