Using AI to screen for adrenal nodules on low-dose chest CT
Official title: The Application of Artificial Intelligence in Screening Adrenal Nodules in Low-dose Chest CT
Run by Peking University First Hospital · NCT07198152 · Data updated 2026-11-12
This project will try an AI tool to find adrenal nodules on routine low-dose chest CT scans for adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Peking University First Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | December 30, 2026 |
| Study ends | January 30, 2027 |
| Registry record updated | September 30, 2025 |
| Trial ID | NCT07198152 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults (over 18) who undergo routine low-dose chest CT scans with diagnostic-quality images and no history of malignant tumors.
✕Probably not a fit
People with prior malignant tumors or with CT images that are too poor in quality or have artifacts would likely not benefit from this screening tool.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will collect routine low-dose chest spiral CT images and extract imaging features from the adrenal gland regions to build a training dataset. They will use those features to train and validate an artificial intelligence algorithm for automatic detection and classification of adrenal nodules. The work is observational and uses existing clinical imaging without adding experimental interventions. Poor-quality images and patients with a history of malignancy will be excluded from the dataset.
Why it matters
Potential benefit: If successful, the AI tool could help detect adrenal nodules more quickly and consistently on routine chest CTs, supporting earlier follow-up and diagnosis.
How similar studies have gone: AI methods have shown promise for detecting incidental findings on CT generally, but AI specifically targeted to adrenal nodules on low-dose chest CT is relatively new and less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The age of the population is over 18 years old, regardless of gender; 2. Images from chest low-dose CT plain scan during routine physical examination; Exclusion Criteria: 1. Patients with a history of malignant tumors; 2. Imaging images with poor quality, artifacts, etc., which make analysis impossible.
Where it's running
-
Peking University First Hospital
Beijing, China Recruiting
Study contacts
- Study coordinator: Shiwei Chen
- Email: 15914944390@163.com
- Phone: +86 159 1494 4390
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.