Using AI to predict outcomes of acute pulmonary embolism
Official title: Prediction of Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography
Run by Shengjing Hospital · NCT05482269 · Data updated 2026-11-12
This study is trying to see if a new AI tool can help predict complications in patients with acute pulmonary embolism based on their CT scans and other health information.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Shengjing Hospital Academic / other |
| Locations | 1 site (Shenyang, Liaoning) |
| Status | Recruiting |
| Started | January 1, 2011 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 11, 2026 |
| Trial ID | NCT05482269 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 years and older diagnosed with pulmonary embolism confirmed by CT pulmonary angiography.
✕Probably not a fit
Patients who are pregnant, have received reperfusion treatment before admission, or have incomplete data regarding key clinical parameters will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to develop a predictive tool using artificial intelligence to assess adverse outcomes in patients diagnosed with acute pulmonary embolism based on CT pulmonary angiography. It collects clinical, laboratory, and imaging data from patients upon admission and follows them for 30 days to predict potential complications. Patients are divided into derivation and validation cohorts to create and test a multivariable logistic regression model, comparing its effectiveness to existing risk stratification systems.
Why it matters
Potential benefit: If successful, this tool could significantly improve the prediction of adverse outcomes in patients with acute pulmonary embolism, leading to better clinical management.
How similar studies have gone: While the use of AI in predicting clinical outcomes is an emerging field, similar studies have shown promise in other areas of medicine, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age of ≥ 18 years and a pulmonary embolism diagnosis based on CT pulmonary angiography Exclusion Criteria: * pregnancy * reception of reperfusion treatment before admission * missing data regarding CT parameters, echocardiography, cardiac troponin I (c-Tn I), and N-terminal-pro brain natriuretic peptide (NT-pro BNP) levels.
Where it's running
-
Shengjing Hospital
Shenyang, Liaoning, China Recruiting
Study contacts
- Principal investigator: Dong Jia — Shengjing Hospital
- Study coordinator: Dong Jia
- Email: jiadong0101@126.com
- Phone: +86-18940252800
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Predicting adverse outcomes in patients with acute pulmonary embolism using CT scans
This study is trying to see if using CT scans and other information can help doctors predict serious problems in patients with acute pulmonary embolism within 30 days of being admitted to the hospital.
-
Orientation Intervention to Rapid Response Teams (ORIENT-RRT) for New Graduate Nurses
The study tests a 12-hour orientation program with a rapid response nurse to see if it improves knowledge, confidence, and nursing practices for new graduate nurses on acute care units.
-
Home-based assessment and treatment to avoid hospital admission for nursing home residents
This study tests whether on-site care by municipal teams can safely reduce hospital visits for nursing home residents who become acutely ill or deteriorate after hours.
-
Thrombectomy for pulmonary embolism in moderately to severely ill patients
This registry tests how well catheter-based thrombectomy works for patients with acute pulmonary embolism who are at intermediate or high risk.
-
Bedside electrical imaging of lung blood flow during clot-removal surgery for CTEPH
We will test whether bedside electrical impedance tomography (EIT) can measure regional lung blood flow before and after pulmonary thromboendarterectomy in people with chronic thromboembolic pulmonary hypertension.
-
Using apixaban to treat blood clots in cancer patients with low platelet counts
This study is testing if a new dose of the blood thinner apixaban can safely help cancer patients with low platelet counts manage blood clots without causing more bleeding.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.