Using AI to predict delirium after surgery in older adults
Using EMR Data and AI to Develop a Passive Digital Marker to Predict Postoperative Delirium
This study is testing if a new digital tool can help predict the risk of confusion after surgery in older adults aged 65 and up who are having major abdominal surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Trial ID | NCT06216483 on ClinicalTrials.gov |
What this trial studies
This pilot randomized controlled trial aims to evaluate the effectiveness of a digital marker for predicting the risk of postoperative delirium in patients aged 65 and older undergoing major abdominal surgery. Participants will be recruited from a university-based surgical practice and will be randomized to receive either the digital marker alert or usual care. The study will assess the incidence of delirium and the long-term cognitive outcomes following surgery. Eligible patients must have a planned inpatient stay of at least 24 hours post-surgery.
Who should consider this trial
Good fit: Ideal candidates are English-speaking individuals aged 65 and older scheduled for major abdominal surgery requiring at least one day of inpatient care.
Not a fit: Patients with severe mental illness, cognitive impairment, or those currently experiencing alcohol or drug withdrawal may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of postoperative delirium and improve long-term cognitive health in older surgical patients.
How similar studies have performed: Other studies have shown promise in using digital markers and AI for predicting postoperative complications, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 65 years old Planned inpatient major surgery requiring inpatient stay ≥ 1 day Exclusion Criteria: * Baseline cognitive impairment or a diagnosis of Alzheimer's Disease/Alzheimer's Disease and Related Dementias (AD/ADRD) * Alcohol or drug withdrawal * Prisoner status * Unable to communicate with research staff due to sensory impairments * Not fluent in English * Currently has a personal safety attendant
Where this trial is running
Indianapolis, Indiana
- Indiana University Health University Hospital — Indianapolis, Indiana, United States (Recruiting)
Study contacts
- Study coordinator: Sanjay Mohanty
- Email: mohantys@iu.edu
- Phone: 317-963-1449
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.