Using AI to predict biological age from health records

Predicting Biological Age Using Electronic Health Records: An AI-Based Approach

Observational The Eye Hospital of Wenzhou Medical University · NCT06791486

This study is testing if an AI tool can use health records to predict a person's biological age and help identify health risks for better patient care.

Quick facts

Study typeObservational
Enrollment1000000 (estimated)
Ages0 Years to 100 Years
SexAll
SponsorThe Eye Hospital of Wenzhou Medical University Academic / other
Locations4 sites (Guangzhou, Guangdong and 3 other locations)
Trial IDNCT06791486 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the effectiveness of an AI-assisted predictive model to estimate biological age using electronic health records (EHR). By analyzing various health data points, including medical history and laboratory results, the study aims to compare biological age with chronological age to assess the model's accuracy. The goal is to identify age-related health risks and improve patient care through personalized healthcare strategies. This multi-center approach integrates diverse patient data to enhance diagnostic accuracy and optimize clinical workflows.

Who should consider this trial

Good fit: Ideal candidates include patients with comprehensive EHR data and no significant cognitive impairments.

Not a fit: Patients with incomplete EHR data or severe cognitive disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved identification of age-related health risks and more personalized healthcare interventions.

How similar studies have performed: While the application of AI in predicting biological age is a novel approach, similar studies have shown promise in enhancing predictive accuracy in healthcare.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients with comprehensive and accessible EHR data, including medical history, laboratory results, treatment data, imaging data (if available), and lifestyle factors (e.g., smoking, physical activity, diet).
2. Patients with no significant cognitive impairments that would prevent them from providing informed consent or participating in the study.
3. All participants must provide informed consent for the use of their medical data for research purposes.

Exclusion Criteria:

1. Patients with incomplete or missing critical EHR data such as medical history, laboratory results, or treatment data that are necessary for predicting biological age.
2. atients with severe cognitive disorders (e.g., dementia, significant mental disabilities) who are unable to provide informed consent or participate meaningfully in the study.
3. Patients with terminal illnesses or those with limited life expectancy where biological age predictions may not be relevant for the purposes of the study.

Where this trial is running

Guangzhou, Guangdong and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Biological Ageelectronic health recordsAI predictionaging
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.