Using AI to improve detection of skin cancer with imaging technology

AI-aided Optical Coherence Tomography for the Detection of Basal Cell Carcinoma

Observational Maastricht University Medical Center · NCT05817279

This study is testing if using artificial intelligence can help doctors more accurately detect skin cancer, specifically Basal Cell Carcinoma, by looking at special scans.

Quick facts

Study typeObservational
Enrollment124 (estimated)
Ages18 Years and up
SexAll
SponsorMaastricht University Medical Center Academic / other
Locations1 site (Maastricht, Limbrug)
Trial IDNCT05817279 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of artificial intelligence in enhancing the diagnostic accuracy of Optical Coherence Tomography (OCT) for detecting Basal Cell Carcinoma (BCC). OCT assessors will review OCT scans of BCC lesions both with and without the assistance of a clinical decision support system (CDSS) to determine if AI can improve diagnostic certainty. The study will include a total of 124 scans, comparing the confidence levels and accuracy of diagnoses made with and without AI support. The goal is to assess whether AI can lead to more reliable and non-invasive cancer detection.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have undergone both an OCT scan and a punch biopsy for an equivocal BCC lesion.

Not a fit: Patients who are unable to provide informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate and non-invasive diagnoses of Basal Cell Carcinoma, reducing the need for invasive biopsies.

How similar studies have performed: Other studies have shown promise in using AI to enhance diagnostic imaging, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients (18+ years)
* Patient underwent OCT scan and punch biopsy for an equivocal BCC lesion

Exclusion Criteria:

- Patient unable to sign informed consent

Where this trial is running

Maastricht, Limbrug

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Basal Cell CarcinomaOptical Coherence TomographyBasal cell carcinomaBCCOptical coherence tomographyOCTImagingArtificial intelligence
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.