Using AI to Improve Cognitive Behavioral Therapy

Enhancing the Quality of CBT in Community Mental Health Through AI-generated Fidelity Feedback

Not applicable Interventional University of Pennsylvania · NCT05340738

This study is testing a new AI tool called LyssnCBT to see if it can make Cognitive Behavioral Therapy better for people receiving treatment in community mental health clinics.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1957 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Pennsylvania Academic / other
Locations1 site (Philadelphia, Pennsylvania)
Trial IDNCT05340738 on ClinicalTrials.gov

What this trial studies

This study aims to enhance the quality of Cognitive Behavioral Therapy (CBT) by implementing a technology called LyssnCBT, developed by researchers at the University of Pennsylvania and Lyssn.io, Inc. The study will first conduct a pilot trial with therapists and supervisors at a community mental health clinic, where therapists will use the LyssnCBT platform with clients and receive fidelity feedback. Following this, a larger randomized stepped-wedge study will compare the effectiveness of LyssnCBT against standard care across multiple clinics over 18 months. Data will be collected on the usage of the platform and therapists' experiences to refine the software and protocols.

Who should consider this trial

Good fit: Ideal candidates for this study include adults receiving therapy for mental health disorders who are willing to participate in research and allow their session recordings to be used.

Not a fit: Patients who are not comfortable with their therapy sessions being recorded or who do not speak English may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the delivery and effectiveness of CBT for patients with mental health disorders.

How similar studies have performed: Other studies have shown promise in using technology to enhance psychotherapy, but this specific approach with LyssnCBT is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Therapists

* Able to participate in therapy sessions conducted in English
* Employed at a Philadelphia CMH treatment center that allows the recruitment and participation of therapists in research-related activities
* Willing to allow their session recordings to be used for research purposes
* Computer and internet access

Supervisors

* Oversee participating therapists
* Computer and internet access

Clients

* Able to participate in therapy sessions conducted in English
* Willing to allow the team to collect data and use their session recordings for research purposes

Exclusion Criteria:

* Unwilling to allow the research team to access their therapy session recordings

Where this trial is running

Philadelphia, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cognitive Behavioral TherapyTherapydepressioncognitive behavioral therapytherapyevidence-based psychotherapytrainingcommunity mental health
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.