Using AI to detect coronary artery calcium for better heart disease prevention
AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention: A Multicenter Randomized Trial
This study tests if using an AI tool to spot calcium buildup in heart arteries can help doctors provide better preventive care for patients at risk of heart disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1500 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Trial ID | NCT06235112 on ClinicalTrials.gov |
What this trial studies
This trial aims to evaluate whether informing clinicians about the presence and quantity of coronary artery calcifications (CAC) through an AI platform can lead to improved preventive care for patients at risk of cardiovascular disease. The study will utilize a cloud-based AI system that analyzes non-contrast chest CT scans to assess CAC levels. By providing this information, the trial seeks to encourage the initiation or intensification of preventive therapies among eligible patients. It is a multicenter randomized trial involving Brigham and Women's Hospital and other locations.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40-75 who have had a chest CT scan within the last three years.
Not a fit: Patients with a history of coronary artery disease, cancer, or other life-limiting conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance cardiovascular disease prevention strategies for at-risk patients.
How similar studies have performed: Other studies have shown promise in using AI for medical imaging analysis, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 40-75 with prior chest CT within last 3 years Exclusion Criteria: * Prior coronary artery disease * Prior cancer * Other life-limiting condition
Where this trial is running
Boston, Massachusetts
- Brigham and Women's Hospital — Boston, Massachusetts, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.