Using advanced ultrasound to diagnose fetal nervous system issues
Role of New High Resolution Ultrasonographic Modalities for Diagnosis of Fetal Nervous System Anomalies
This study tests if advanced ultrasound can help spot brain problems in unborn babies during mid-pregnancy to improve care and outcomes for low-risk pregnancies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 20 Years to 28 Years |
| Sex | Female |
| Sponsor | Woman's Health University Hospital, Egypt Academic / other |
| Locations | 1 site (Assiut) |
| Trial ID | NCT05771922 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the use of high-resolution ultrasonography to evaluate the fetal central nervous system (CNS) during mid-trimester scans in low-risk pregnancies. It aims to assess the anatomical integrity of the fetal brain by examining key structures through specific axial planes. The study is particularly important for identifying congenital CNS malformations, which can significantly impact the health and development of the fetus. By improving detection methods, the study seeks to provide better guidance for pregnancy management and potential interventions.
Who should consider this trial
Good fit: Ideal candidates for this study include pregnant individuals with a suspicion of CNS or spinal malformations based on routine ultrasound screenings.
Not a fit: Patients with low-risk pregnancies are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance early detection of fetal CNS anomalies, leading to improved outcomes for affected infants.
How similar studies have performed: Other studies have shown success in using advanced imaging techniques for prenatal diagnosis, indicating that this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Suspicion of CNS or spinal malformation at routine screening ultrasound Suspicion of CNS or spinal malformation at nuchal translucency scan Family history of inheritable CNS spinal malformations Previous pregnancy complicated by fetal brain or spinal malformation Fetus with congenital heart disease Monochorionic twins Suspected congenital intrauterine infection Exposure to teratogens known to affect neurogenesis Exclusion Criteria: Low risk pregnancy
Where this trial is running
Assiut
- Woman's Health University Hospital — Assiut, Egypt (Recruiting)
Study contacts
- Study coordinator: Atef Darwish, Prof
- Email: atef_darwish@yahoo.com
- Phone: 0201001572723
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.