Using advanced MRI to evaluate facial nerves in parotid tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to improve the evaluation of facial nerves during parotidectomy for patients with parotid neoplasms by utilizing high-resolution 3D MRI neurogram sequences. The researchers will recruit patients diagnosed with parotid tumors through other imaging methods and assess the efficacy of these advanced MRI techniques in visualizing the intra-parotid facial nerves. The goal is to reduce the risk of nerve injury during surgery, which can lead to temporary or permanent facial paralysis. The study will involve patients from an ear, nose, and throat specialty clinic who meet specific inclusion criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Consecutive patients with parotid tumour diagnosed on other imaging modalities (such as ultrasonography or computed tomography), with or without cytological diagnosis from fine needle aspiration, will be recruited from the ear, nose and throat specialty clinic.

Exclusion Criteria:

* Patients who are contraindicated to magnetic resonance imaging (such as due to underlying MRI incompatible metallic implants)
* Patient who are contraindicated to MRI contrast agents (such as advanced renal failure or previous severe allergic reaction)
* Patients who cannot cooperate for MRI scanning.
* Patients show are unable to provide informed consent.

Where it's running

• Gerald Choa MRI Center
  Hong Kong, Hong Kong Recruiting

Study contacts

• Principal investigator: Ho Sang Leung, MBBS (HK) — Department of Imaging and Interventional Radiology, Prince of Wales Hospital
• Study coordinator: Gerald Choa MRI Center CUHK
• Email: cumri@cuhk.edu.hk
• Phone: 852-35051009

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Parotid gland surgery without wound drains: can patients go home the same day?

  This study tests whether skipping a wound drain during parotidectomy is as safe as the usual drainage approach for adults in Sweden.

  Recruiting at 3 sites Uppsala University Hospital · Stockholm and 2 other locations · NCT07620184

• Intraparotid injection of bupivacaine with dexamethasone after partial parotidectomy

  This early-phase study tests whether a single intraparotid injection of bupivacaine with dexamethasone is safe and tolerable after partial parotidectomy for a benign tumor.

  Recruiting Early Phase 1 Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT07812259

• Proton beam therapy for parotid cancer after surgery

  This study tests whether proton beam therapy after surgery can reduce side effects and improve outcomes for adults with malignant parotid gland cancer.

  Recruiting at 2 sites The Christie NHS Foundation Trust · London and 1 other locations · NCT06421649

• Using MRI to assess parotid tumors before surgery

  This study is testing if a special type of MRI can help doctors see how close parotid tumors are to the facial nerve before surgery to improve patient outcomes.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris, PARIS · NCT04613349

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.