Using advanced MRI to evaluate facial nerves in parotid tumors
Application of 3D Magnetic Resonance Neurogram Sequences for Evaluation of Intraparotid Facial Nerves in Patients With Parotid Neoplasm
NA · Chinese University of Hong Kong · NCT05296109
This study is testing if a new type of MRI can help doctors see facial nerves better during surgery for parotid tumors to reduce the risk of nerve damage.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chinese University of Hong Kong (other) |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT05296109 on ClinicalTrials.gov |
What this trial studies
This study aims to improve the evaluation of facial nerves during parotidectomy for patients with parotid neoplasms by utilizing high-resolution 3D MRI neurogram sequences. The researchers will recruit patients diagnosed with parotid tumors through other imaging methods and assess the efficacy of these advanced MRI techniques in visualizing the intra-parotid facial nerves. The goal is to reduce the risk of nerve injury during surgery, which can lead to temporary or permanent facial paralysis. The study will involve patients from an ear, nose, and throat specialty clinic who meet specific inclusion criteria.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with parotid tumors who are eligible for MRI and can provide informed consent.
Not a fit: Patients with contraindications to MRI or those unable to cooperate during the scanning process may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of facial nerve injuries during parotid surgery.
How similar studies have performed: While traditional imaging has limitations, advancements in MRI techniques suggest potential for success, although this specific application may be novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients with parotid tumour diagnosed on other imaging modalities (such as ultrasonography or computed tomography), with or without cytological diagnosis from fine needle aspiration, will be recruited from the ear, nose and throat specialty clinic. Exclusion Criteria: * Patients who are contraindicated to magnetic resonance imaging (such as due to underlying MRI incompatible metallic implants) * Patient who are contraindicated to MRI contrast agents (such as advanced renal failure or previous severe allergic reaction) * Patients who cannot cooperate for MRI scanning. * Patients show are unable to provide informed consent.
Where this trial is running
Hong Kong
- Gerald Choa MRI Center — Hong Kong, Hong Kong (RECRUITING)
Study contacts
- Principal investigator: Ho Sang Leung, MBBS (HK) — Department of Imaging and Interventional Radiology, Prince of Wales Hospital
- Study coordinator: Gerald Choa MRI Center CUHK
- Email: cumri@cuhk.edu.hk
- Phone: 852-35051009
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parotid Neoplasms