Using advanced imaging to improve chest wall surgery precision
Intraoperative Navigation for Surgically Precise Resection of the Chest (INSPIRE)
This study is testing whether using real-time 3D imaging during chest wall surgery can help surgeons work more accurately and improve recovery for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Health Network, Toronto Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT04328584 on ClinicalTrials.gov |
What this trial studies
This study focuses on enhancing the precision of chest wall resections by integrating real-time 3D imaging with intraoperative findings. By utilizing a surgical navigation system, surgeons can obtain better anatomical references during surgery, potentially reducing the need for reoperations and improving surgical outcomes. The study will enroll twenty patients scheduled for chest wall resection at Toronto General Hospital over a two-year period. Participants will consent to the use of intraoperative imaging to guide their surgical procedure.
Who should consider this trial
Good fit: Ideal candidates are adults scheduled for surgical resection of a chest wall lesion who can provide informed consent.
Not a fit: Patients with unresectable lesions, unstable conditions, or those with metallic implants that may interfere with imaging will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more precise surgical resections and improved patient outcomes in chest wall surgeries.
How similar studies have performed: Other studies utilizing surgical navigation systems have shown promise in improving surgical precision, indicating that this approach is supported by prior successful methodologies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Ability to provide informed consent 2. Scheduled to undergo surgical resection of a chest wall lesion 3. At least 18 years of age 4. Must sign and be given a copy of the written informed consent form Exclusion Criteria: 1. Unresectable lesions or unstable patient condition, for which surgery is not recommended 2. Participants with metallic implantation, such as ribs fixations, a pacemaker, or pedicle screws, which may affect the accuracy of CBCT 3. Excluded at the discretion of the clinical investigator/surgeon, if they are enrolled in other studies that will result in combined radiation exposure exceeding standard of care 4. Pregnant, lactating, or planning to become pregnant during the period of the evaluation
Where this trial is running
Toronto, Ontario
- Toronto General Hospital — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Study coordinator: Judy McConnell
- Email: judy.mcconnell@uhn.ca
- Phone: 4165817486
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.