Using advanced imaging techniques to improve gastric cancer staging
Official title: Diagnostic Accuracy of Multi-parametric MRI and Dual-energy CT in Gastric Cancer: a Paired Validating Confirmatory Study
Run by The First Affiliated Hospital with Nanjing Medical University · NCT05508126 · Data updated 2026-11-12
This study is testing whether advanced imaging techniques can help doctors better stage gastric cancer in patients before surgery to improve their treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 222 (estimated) |
| Sponsor | The First Affiliated Hospital with Nanjing Medical University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Nanjing) |
| Status | Recruiting |
| Started | November 1, 2021 |
| Main results expected | June 1, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | October 15, 2024 |
| Trial ID | NCT05508126 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with preoperative pathologically confirmed gastric cancer who have not received prior treatment.
✕Probably not a fit
Patients with recurrent gastric cancer or those who have previously undergone therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the effectiveness of multi-parametric magnetic resonance imaging (mpMRI) and dual-energy computed tomography (DECT) in accurately staging gastric cancer before surgery. Gastric cancer is a leading cause of cancer-related deaths, and precise staging is crucial for determining the appropriate treatment. The study will include patients with confirmed gastric cancer who have not undergone prior therapy, utilizing advanced imaging techniques to enhance diagnostic accuracy. The findings could lead to improved individualized treatment plans based on more reliable staging results.
Why it matters
Potential benefit: If successful, this study could lead to more accurate preoperative staging of gastric cancer, allowing for better treatment decisions and improved patient outcomes.
How similar studies have gone: While the use of DECT and mpMRI in gastric cancer staging is gaining traction, this study explores their combined diagnostic performance, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients with preoperative pathologically confirmed GC by endoscopy and preoperative imaging data (DECT/mpMRI) were included. * No contraindications for CT/MRI examination * Written informed consent Exclusion Criteria: * Patients with a history of previous therapy. * Patients with recurrent gastric cancer * Patients with a history of severe allergy to contrast agents * Patients with imaging artefacts affect the evaluation
Where it's running
-
Yu-Dong Zhang
Nanjing, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.