Using advanced imaging techniques to improve gastric cancer staging
Diagnostic Accuracy of Multi-parametric MRI and Dual-energy CT in Gastric Cancer: a Paired Validating Confirmatory Study
This study is testing whether advanced imaging techniques can help doctors better stage gastric cancer in patients before surgery to improve their treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 222 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The First Affiliated Hospital with Nanjing Medical University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Nanjing) |
| Trial ID | NCT05508126 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of multi-parametric magnetic resonance imaging (mpMRI) and dual-energy computed tomography (DECT) in accurately staging gastric cancer before surgery. Gastric cancer is a leading cause of cancer-related deaths, and precise staging is crucial for determining the appropriate treatment. The study will include patients with confirmed gastric cancer who have not undergone prior therapy, utilizing advanced imaging techniques to enhance diagnostic accuracy. The findings could lead to improved individualized treatment plans based on more reliable staging results.
Who should consider this trial
Good fit: Ideal candidates are patients with preoperative pathologically confirmed gastric cancer who have not received prior treatment.
Not a fit: Patients with recurrent gastric cancer or those who have previously undergone therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate preoperative staging of gastric cancer, allowing for better treatment decisions and improved patient outcomes.
How similar studies have performed: While the use of DECT and mpMRI in gastric cancer staging is gaining traction, this study explores their combined diagnostic performance, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients with preoperative pathologically confirmed GC by endoscopy and preoperative imaging data (DECT/mpMRI) were included. * No contraindications for CT/MRI examination * Written informed consent Exclusion Criteria: * Patients with a history of previous therapy. * Patients with recurrent gastric cancer * Patients with a history of severe allergy to contrast agents * Patients with imaging artefacts affect the evaluation
Where this trial is running
Nanjing
- Yu-Dong Zhang — Nanjing, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.