Using advanced imaging techniques to improve diagnosis and management of gastric cancer
Diagnostic and Predictive Performance of Dual-/ Muti- Energy CT and MRI in the Treatment Response and Survival Prognosis of Gastric Cancer
This study is testing whether advanced imaging techniques can help doctors better diagnose and manage gastric cancer in patients who are about to have surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The First Affiliated Hospital of Zhengzhou University Academic / other |
| Locations | 1 site (Zhengzhou, China) |
| Trial ID | NCT06869694 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the preoperative assessment of gastric cancer by evaluating the effectiveness of multi-parametric magnetic resonance imaging (mpMRI) and advanced CT techniques, including Dual-/Multi-energy CT and photon-counting Detector CT (PCD-CT). By accurately predicting risk stratification, treatment response, and survival prognosis, the study seeks to inform clinical treatment decisions and ultimately improve patient outcomes. Participants will include patients with confirmed gastric cancer who are undergoing surgical procedures. The study will analyze imaging results to determine their impact on management strategies.
Who should consider this trial
Good fit: Ideal candidates are patients with a pathological biopsy-confirmed diagnosis of gastric cancer who are scheduled for radical gastrectomy.
Not a fit: Patients who refuse to sign informed consent or have poor-quality imaging that cannot provide clear results may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and better treatment planning for patients with gastric cancer.
How similar studies have performed: Other studies utilizing advanced imaging techniques for cancer diagnosis have shown promising results, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Pathological biopsy confirmed gastric cancer; 2. Surgery: patients undergoing radical gastrectomy. Patients undergoing exploratory abdominal surgery or palliative tumor resection were still included in the study when peritoneal metastasis or adjacent organ invasion was identified intraoperatively and radical surgical resection was not possible. Exclusion Criteria: 1. Refusal or inability to sign informed consent; 2. CT or MRI images are poor or the focus is small and CT images are not clear; 3. Patients with other tumors complicated with patients with important organ dysfunction.
Where this trial is running
Zhengzhou, China
- The First Affiliated Hospital of Zhengzhou University — Zhengzhou, China, China (Recruiting)
Study contacts
- Study coordinator: Zihao Zhao, Dr
- Email: zzh2020@163.com
- Phone: 0371-66271387
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.