Using advanced imaging for targeted prostate cancer biopsies
MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research
This study is testing if advanced imaging can help doctors take better biopsies of prostate cancer to better understand how the disease is progressing in patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Male |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (New Haven, Connecticut) |
| Trial ID | NCT02313623 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate prostate needle-core biopsies through single-cell analysis, focusing on proteomic and phenotypic signatures. By utilizing advanced imaging techniques, the study seeks to improve the prediction of malignant progression in prostate cancer patients. Participants will undergo a prostate fusion biopsy, which is a minimally invasive procedure, allowing for comprehensive analysis of biopsy samples. The goal is to generate new insights into prostate tumor progression beyond traditional pathological examinations.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for an Artemis prostate biopsy with defined regions of interest.
Not a fit: Patients unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate predictions of prostate cancer progression and better patient management.
How similar studies have performed: While similar approaches have been explored, this specific method of single-cell analysis in prostate cancer biopsies is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Only subjects that have scheduled Artemis prostate biopsy with defined regions of interest will be included in this study Exclusion Criteria: * Any subjects that are unable to provide informed consent will be excluded
Where this trial is running
New Haven, Connecticut
- Yale University — New Haven, Connecticut, United States (Recruiting)
Study contacts
- Principal investigator: Preston C Sprenkle, MD — Yale University
- Study coordinator: Preston Sprenkle, MD
- Email: Preston.Sprenkle@yale.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.