Using advanced imaging and navigation techniques in orthopedic surgery for tumors

Orthopedic Oncology Surgery: Navigation, Intraoperative Imaging and Virtual Reality

Observational Regina Elena Cancer Institute · NCT05918536

This study is testing if using advanced imaging during orthopedic surgeries for tumors can help doctors achieve better surgical results for patients needing surgery or amputation.

Quick facts

Study typeObservational
Enrollment45 (estimated)
SexAll
SponsorRegina Elena Cancer Institute Academic / other
Locations1 site (Rome)
Trial IDNCT05918536 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the quality of surgical margins achieved during orthopedic surgeries for musculoskeletal neoplasms using navigated intraoperative CT imaging. It involves patients who require surgical resection or amputation due to their condition, with preoperative planning discussed in a multidisciplinary team. The study aims to assess how these advanced imaging techniques can improve surgical outcomes without introducing any new interventions.

Who should consider this trial

Good fit: Ideal candidates include patients of any age with musculoskeletal neoplasms located in complex anatomical sites who are scheduled for surgical intervention.

Not a fit: Patients who are unable to undergo pre- and post-treatment assessments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and reduced recurrence rates for patients with musculoskeletal tumors.

How similar studies have performed: Other studies utilizing advanced imaging techniques in surgical oncology have shown promising results, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: no limit
* Patients with musculoskeletal neoplasms predominantly in complex sites
* Patients who will have to undergo surgical resection/amputation for the management of their clinical case
* Preparation of preoperative planning discussed at DMT
* Surgery performed with the aid of Intraoperative CT Navigated
* Written informed consent

Exclusion Criteria:

- Inability to perform pre-post treatment assessment

Where this trial is running

Rome

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions NeoplasmsMuscle Neoplasm
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.