Using acupuncture to treat dementia after a stroke

The Role of Acupuncture-induced Exosome in Treating Post-stroke Dementia

Not applicable Interventional China Medical University Hospital · NCT05326724

This study is testing if acupuncture can help improve thinking and memory in people who have had a stroke and are dealing with dementia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages50 Years to 75 Years
SexAll
SponsorChina Medical University Hospital Academic / other
Locations1 site (Taichung, North District)
Trial IDNCT05326724 on ClinicalTrials.gov

What this trial studies

This study investigates the potential of acupuncture-induced exosomes in treating post-stroke dementia, a condition that affects a significant number of stroke survivors. It aims to explore how exosomes, which are small extracellular vesicles involved in cell communication, may play a role in cognitive recovery following a stroke. The study will involve patients with a history of stroke and specific cognitive impairment levels, utilizing acupuncture as the primary intervention to potentially enhance recovery. The research seeks to provide insights into a novel therapeutic approach for a condition that currently has limited treatment options.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with a history of stroke and a Mini-Mental State Examination (MMSE) score between 16 and 26.

Not a fit: Patients with serious comorbid conditions, intolerance to acupuncture, or allergies to acupuncture needles may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could offer a new, effective treatment option for patients suffering from post-stroke dementia.

How similar studies have performed: While acupuncture has been explored in various contexts, the specific use of acupuncture-induced exosomes for post-stroke dementia is a novel approach that has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. History of stroke.
2. MMSE score between 16 and 26.

Exclusion Criteria:

1. Those with serious diseases, such as heart failure, chronic failure or cancer patients, etc.
2. Intolerance to acupuncture treatment.
3. Allergy to acupuncture needles.
4. Refusal to sign the informed consent form.

Where this trial is running

Taichung, North District

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ExosomePost-stroke DementiaAcupuncture
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.