Using active anterior rhinomanometry to guide when surgery is needed for nasal obstruction.

Evaluation of the Reliability of Anterior Active Rhinomanometry as an Independent Tool for Surgical Indication in Nasal Obstruction

This test will try whether preoperative rhinomanometry can help decide if adults with nasal obstruction should have septoplasty, turbinate reduction, or rhinoplasty.

Quick facts

• Study type: Observational
• Enrollment: 200 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (Academic / other)
• Locations: 1 site (Draguignan, Var)
• Trial ID: NCT07379775 on ClinicalTrials.gov

What this trial studies

This observational study collects preoperative active anterior rhinomanometry (AAR) measurements in adults scheduled for surgical correction of nasal obstruction to determine whether AAR can independently indicate the need for surgery. Participants are adults with nasal obstruction who underwent rhinomanometry and are scheduled for septoplasty ± turbinoplasty ± rhinoplasty; patients with nasal polyps, certain chronic rhinosinusitis forms, or sinonasal tumors are excluded. Investigators will compare AAR results with clinical findings and standard patient-reported outcome scores (for example VAS, NOSE, SNOT-22) to judge whether AAR alone reliably identifies surgical candidates. The protocol is conducted at a regional hospital in Draguignan, France.

Who should consider this trial

Good fit: Adults (≥18 years) with nasal obstruction who are already scheduled for septoplasty, turbinate reduction, or rhinoplasty and who had preoperative rhinomanometry and consent to participate.

Not a fit: Patients with nasal polyps, chronic edematous or crusting rhinosinusitis, or current/past sinonasal tumors — who are excluded from this protocol — are unlikely to benefit from AAR as tested here.

Why it matters

Potential benefit: If successful, this could give doctors a simple objective test to standardize surgical decisions and reduce unnecessary or ineffective nasal surgeries.

How similar studies have performed: Rhinomanometry is a well-established objective measure used alongside symptoms and imaging, but relying on it alone as the sole indication for surgery is not widely validated in prior work.

Eligibility criteria

Inclusion Criteria:

1. Patients aged 18 years or older with nasal obstruction (NO).
2. Patients scheduled for surgery: septoplasty ± turbinoplasty ± rhinoplasty for nasal obstruction.
3. Patients who have undergone a preoperative rhinomanometry assessment.
4. Patients consented to participation

Exclusion Criteria:

1. Nasal polyps.
2. Chronic edematous-purulent rhinosinusitis (e.g., cystic fibrosis).
3. Crusting rhinosinusitis (e.g., sarcoidosis, granulomatosis with polyangiitis \[Wegener's\]).
4. Current or previously treated nasal or sinus tumors, or patients undergoing tumor work-up

Where this trial is running

Draguignan, Var

• Centre Hospitalier de la Dracénie — Draguignan, Var, France (Recruiting)

Study contacts

• Study coordinator: Sophie Lafond

Conditions Nasal Obstruction