Using action observation and motor imagery therapy to help stroke recovery
Official title: Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Stroke, Randomized Controlled Trial
Run by Karamanoğlu Mehmetbey University · NCT06166862 · Data updated 2026-11-12
This study is testing if watching movements and imagining doing them can help stroke patients recover their motor skills better than just regular rehab alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Karamanoğlu Mehmetbey University Academic / other |
| Locations | 1 site (Karaman, Karaman) |
| Status | Recruiting |
| Started | December 12, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | August 5, 2026 |
| Trial ID | NCT06166862 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients who have experienced a stroke within the last year and have a Functional Ambulation Classification score between 2 and 5.
✕Probably not a fit
Patients with repeated strokes, cognitive dysfunction, or severe sensory impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of action observation (AO) and motor imagery (MI) therapies in enhancing motor recovery for stroke patients. These therapies leverage the mirror neuron system to promote motor learning by allowing patients to observe and visualize movements. Participants will receive AO and MI therapy in addition to standard rehabilitation programs to assess improvements in motor function, daily living activities, and overall quality of life. The study aims to determine if these innovative therapies provide additional benefits compared to conventional rehabilitation alone.
Why it matters
Potential benefit: If successful, this approach could significantly enhance recovery outcomes and quality of life for stroke patients.
How similar studies have gone: Previous studies have shown promising results using similar therapies, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who had a stroke in the last year * Functional Ambulation Classification score 2-5 Exclusion Criteria: * Patients who have had repeated strokes * Patients with neglect * Patients with cognitive dysfunction (those who cannot follow simple verbal instructions) * Patients with severe hearing problems * Patients with severe vision problems * Patients with additional musculoskeletal system pathology that will affect physical performance (such as amputation, severe joint mobility limitation, peripheral nerve damage) * Patients with uncontrolled hypertension and diabetes mellitus * Patients with a history of symptomatic lung disease (such as asthma, chronic obstructive pulmonary disease, emphysema) * Patients with a history of symptomatic cardiac disease (such as coronary artery disease, arrhythmia, heart failure) * Patients with peripheral artery disease
Where it's running
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Karaman Training and Research Hospital
Karaman, Karaman, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Yurdagul Bahran Mustu, MD. — Karaman Training and Research Hospital
- Study coordinator: Yurdagul Bahran Mustu, MD.
- Email: yurdagulbahran@gmail.com
- Phone: +90 506 209 76 72
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.