Using action observation and motor imagery therapy to help people with Parkinson's disease

Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Parkinson's Disease, Randomized Controlled Trial

NA · Karamanoğlu Mehmetbey University · NCT06154356

This study tests if combining action observation and motor imagery therapy with regular rehab can help people with Parkinson's disease improve their balance and quality of life.

Quick facts

PhaseNA
Study typeInterventional
Enrollment54 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorKaramanoğlu Mehmetbey University (other)
Locations1 site (Karaman, Karaman)
Trial IDNCT06154356 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of action observation (AO) and motor imagery (MI) therapies in enhancing rehabilitation outcomes for patients with Parkinson's disease (PD). The study aims to determine if these therapies, when combined with conventional rehabilitation methods, can improve balance, functional status, and quality of life for individuals suffering from PD. The approach leverages the mirror neuron system, which is activated during both the observation and mental visualization of goal-directed actions, to facilitate motor learning and re-learning. Participants will be assessed for improvements in their rehabilitation outcomes compared to those receiving sham therapy.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with Parkinson's disease who are in Hoehn and Yahr stages 1-3.

Not a fit: Patients with cognitive dysfunction, severe sensory impairments, or other significant health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could significantly enhance the rehabilitation process for patients with Parkinson's disease, leading to improved balance and quality of life.

How similar studies have performed: Previous studies have shown promise in using similar approaches with motor imagery and action observation therapies in rehabilitation, suggesting potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a diagnosis of Parkinson's Disease
* Hoehn and Yahr Stage 1-3

Exclusion Criteria:

* Patients with cognitive dysfunction (those who cannot follow simple verbal instructions)
* Patients with severe hearing problems
* Patients with severe vision problems
* Patients with additional musculoskeletal system pathology that will affect physical performance (such as amputation, severe joint mobility limitation, peripheral nerve damage)
* Patients with uncontrolled hypertension and diabetes mellitus
* Patients with a history of symptomatic lung disease (such as asthma, chronic obstructive pulmonary disease, emphysema)
* Patients with a history of symptomatic cardiac disease (such as coronary artery disease, arrhythmia, heart failure)

Where this trial is running

Karaman, Karaman

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Parkinson's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.