Using action observation and motor imagery therapy to help people with Parkinson's disease
Official title: Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Parkinson's Disease, Randomized Controlled Trial
Run by Karamanoğlu Mehmetbey University · NCT06154356 · Data updated 2026-11-12
This study tests if combining action observation and motor imagery therapy with regular rehab can help people with Parkinson's disease improve their balance and quality of life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Karamanoğlu Mehmetbey University Academic / other |
| Locations | 1 site (Karaman, Karaman) |
| Status | Recruiting |
| Started | December 14, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | August 5, 2026 |
| Trial ID | NCT06154356 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with Parkinson's disease who are in Hoehn and Yahr stages 1-3.
✕Probably not a fit
Patients with cognitive dysfunction, severe sensory impairments, or other significant health issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of action observation (AO) and motor imagery (MI) therapies in enhancing rehabilitation outcomes for patients with Parkinson's disease (PD). The study aims to determine if these therapies, when combined with conventional rehabilitation methods, can improve balance, functional status, and quality of life for individuals suffering from PD. The approach leverages the mirror neuron system, which is activated during both the observation and mental visualization of goal-directed actions, to facilitate motor learning and re-learning. Participants will be assessed for improvements in their rehabilitation outcomes compared to those receiving sham therapy.
Why it matters
Potential benefit: If successful, this therapy could significantly enhance the rehabilitation process for patients with Parkinson's disease, leading to improved balance and quality of life.
How similar studies have gone: Previous studies have shown promise in using similar approaches with motor imagery and action observation therapies in rehabilitation, suggesting potential for success in this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a diagnosis of Parkinson's Disease * Hoehn and Yahr Stage 1-3 Exclusion Criteria: * Patients with cognitive dysfunction (those who cannot follow simple verbal instructions) * Patients with severe hearing problems * Patients with severe vision problems * Patients with additional musculoskeletal system pathology that will affect physical performance (such as amputation, severe joint mobility limitation, peripheral nerve damage) * Patients with uncontrolled hypertension and diabetes mellitus * Patients with a history of symptomatic lung disease (such as asthma, chronic obstructive pulmonary disease, emphysema) * Patients with a history of symptomatic cardiac disease (such as coronary artery disease, arrhythmia, heart failure)
Where it's running
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Karaman Training and Research Hospital
Karaman, Karaman, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Yurdagul Bahran Mustu, MD. — Karaman Training and Research Hospital
- Study coordinator: Yurdagul Bahran Mustu, MD.
- Email: yurdagulbahran@gmail.com
- Phone: +90 506 209 76 72
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.