Using a wearable vest to measure lung fluid in heart failure patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a wearable vest that non-invasively measures lung fluid content in hospitalized patients suffering from acute decompensated heart failure. The approach involves using Remote Dielectric Sensing (ReDS) technology to guide diuresis treatment, which is traditionally managed through less reliable clinical methods. Patients will be randomly assigned to either receive ReDS-guided treatment or usual care, with daily measurements taken for all participants. The goal is to determine if ReDS can improve patient outcomes by providing more accurate assessments of fluid status.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients hospitalized for acute decompensated heart failure requiring treatment with intravenous diuretics and/or IV vasoactive drugs
* Patient has signed informed consent and has authorized use and disclosed health information
* Patient is at least 18 years of age
* Patient physically suitable for ReDS measurement
* GFR\>25
* Initial ReDS Measurement \>35%

Exclusion Criteria:

* Patient characteristics excluded from approved use of ReDS system: height less than 155cm or greater than 190cm, BMI \<22 or \>39, chest circumference \<80cm or \>115cm , or flail chest
* Evidence of focal lung lesions on history, physical exam or chest x-ray, including history of pulmonary embolism, active pneumonia, or known lung nodule
* Chronic renal failure (GFR\<25)
* Prior cardiac surgery within 2 months of index admission
* Patient has a ventricular assist device or has had a cardiac transplantation
* Patients in cardiogenic shock at admission requiring inotropic support
* Congenital heart malformations or intra-thoracic mass that would affect right-lung anatomy (e.g dextrocardia, lung carcinoma, or pacemaker box in the right chest)

Where it's running

• University of California, San Francisco
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Liviu Klein, MD, MS — Director, Mechanical Circulatory Support and Heart Failure Device Program
• Study coordinator: Cynthia Partida-Higuera
• Email: Cynthia.Partida-Higuera@ucsf.edu
• Phone: 415-514-1125

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.