Using a TENS unit to reduce pain after laminaria insertion

Randomized Controlled Trial: TENS Unit To Decrease Pain After Laminaria Insertion

Not applicable Interventional Queen's Medical Center · NCT06529003

This study is testing whether using a TENS unit can help reduce pain for patients getting laminaria inserted before a second-trimester abortion.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages18 Years and up
SexFemale
SponsorQueen's Medical Center Academic / other
Locations1 site (Honolulu, Hawaii)
Trial IDNCT06529003 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of a transcutaneous electrical nerve stimulation (TENS) unit as a non-medication pain relief option for patients undergoing laminaria insertion prior to a second-trimester abortion. Participants will be divided into two groups: one receiving standard care with a placebo and the other using the TENS unit in addition to standard care. The primary focus is to compare maximum pain scores reported during the interval between osmotic dilator placement and the dilation and evacuation (D&E) procedure. Secondary objectives include evaluating pain scores at the time of laminaria insertion, additional analgesic use, and patient satisfaction with pain management.

Who should consider this trial

Good fit: Ideal candidates are women aged 18 and older undergoing laminaria insertion for a D&E procedure.

Not a fit: Patients with contraindications to TENS or those who have recently used adjunctive pharmacologic cervical preparation may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a non-pharmacological option for pain management during a sensitive medical procedure.

How similar studies have performed: While the use of TENS units for pain management is established in other contexts, this specific application in second-trimester abortion is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing laminaria insertion for D\&E procedure
* Age 18 years or older
* Capability and willingness to send and receive SMS messages by phone and complete web-based surveys
* Capability to read and understand directions for using a TENS unit
* Capability to operate a TENS unit according to provided directions

Exclusion Criteria:

* Inability to complete the informed consent in English
* Exposure to adjunctive pharmacologic cervical preparation (misoprostol or mifepristone) within 48 hours of the D\&E procedure
* Contraindication to ibuprofen or bupivacaine
* Contraindication to TENS, including cardiac pacemakers, epilepsy, bleeding disorders, cancer, and concurrent use near transdermal drug delivery systems
* Previous participation in this trial
* Prior use of TENS unit

Where this trial is running

Honolulu, Hawaii

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Second Trimester Abortion
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.