Using a specific position during radiotherapy for left breast cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical study evaluates the effectiveness of the lateral decubitus position in patients with left breast cancer undergoing adjuvant radiotherapy. It is a randomized, non-blind, single-center trial that recruits female patients aged 18-70 with newly diagnosed left-sided breast cancer. Participants will be assigned to either a deep inspiration breath-hold (DIBH) or free breathing (FB) group, with further division based on their ability to tolerate the DIBH technique. The study aims to compare treatment plans developed for patients in different positions to determine the best approach for minimizing radiation exposure to surrounding organs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntary signing of the informed consent form
* Female patients aged 18-70 years
* Newly diagnosed left-sided breast cancer confirmed by histopathology
* No evidence of distant metastasis
* Undergoing modified radical mastectomy or breast-conserving surgery
* ECOG performance status of 0, 1, or 2
* Tolerance to radiotherapy
* Radiation field covering the entire left breast/chest wall ± regional lymphatic drainage area

Exclusion Criteria:

* Bilateral breast cancer at diagnosis
* History of breast reconstruction or implant placement on the affected side
* Prior radiotherapy to the chest or supraclavicular region
* Patients deemed unsuitable for the study based on the investigator's judgment

Where it's running

• Nanfang Hospital, Southern Medical University
  Guangzhou, Guangdong Provinse, China Recruiting
• Nanfang Hospital, Southern Medical University
  Guangzhou, Guangdong Provinse, China Recruiting

Study contacts

• Study coordinator: hongmei Wang, phD
• Email: hongmeiw18@163.com
• Phone: 13189092896

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.