Using a special probe for PET imaging of solid tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop a noninvasive PET/CT imaging technique using a 68Ga-ACN376 probe to detect the expression of CLDN18.2 in solid tumors. By identifying patients with measurable tumor lesions, the study seeks to determine who may benefit from targeted treatments against CLDN18.2. The approach focuses on enhancing the accuracy of tumor characterization and treatment planning for affected individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Aged \>18 years old; ECOG 0 or 1;
* 2\. Patients with solid tumors;
* 3\. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
* 4\. life expectancy \>=12 weeks.

Exclusion Criteria:

* 1\. Significant hepatic or renal dysfunction;
* 2\. Is pregnant or ready to pregnant;
* 3\. Cannot keep their states for half an hour;
* 4\. Refusal to join the clinical study;
* 5\. Suffering from claustrophobia or other mental diseases;
* 6\. Any other situation that researchers think it is not suitable to participate in the experiment.

Where it's running

• Beijing cancer hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Hua Zhu — Peking University Cancer Hospital & Institute
• Study coordinator: Hua Zhu
• Email: zhuhuabch@pku.edu.cn
• Phone: 010-88196495

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.