Using a special orthosis to help infants with trunk control

Assessing Functional Improvements With Use of the SPIO Core-Max Expedition TLSO

Observational Medical College of Wisconsin · NCT06027580

This study is testing if a special support device can help babies with cerebral palsy improve their head, trunk, and arm movements better than just regular therapy alone.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages6 Months to 18 Months
SexAll
SponsorMedical College of Wisconsin Academic / other
Locations1 site (Milwaukee, Wisconsin)
Trial IDNCT06027580 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness of the SPIO® Core-MAX® Expedition orthosis in improving head, trunk, and upper limb function in infants aged 6 to 18 months with abnormal muscle tone due to cerebral palsy. Families will choose between standard therapy or therapy combined with the orthosis, and outcomes will be assessed at baseline, 3 months, and 6 months. The study will compare the functional improvements between the two groups to determine the impact of the orthosis on motor skills.

Who should consider this trial

Good fit: Ideal candidates are infants aged 6 to 18 months with abnormal muscle tone who have not previously used similar orthotic garments.

Not a fit: Patients who have had recent orthopedic or neurosurgery or those who are non-English speaking may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance trunk control and overall motor function in infants with cerebral palsy.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in using orthotic devices for improving motor function in children with cerebral palsy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Study subjects aged 6 months to 18 months age corrected with abnormal muscle tone
* No previous use of SPIO® or similar Lycra/compression garments
* Assessed by provider as likely to benefit from use of compression garment

Exclusion Criteria:

* Non-English speaking
* Inability for family to bring study subject to assessments
* Orthosis or casting that contraindicate SPIO® Core-MAX® during the study period
* Botulinum toxin injections within 3 months, or during study participation
* Having prior orthopedic or neurosurgery surgeries within one year

Where this trial is running

Milwaukee, Wisconsin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cerebral Palsyabnormal muscle tonecerebral palsyhypotoniamuscle tonespasticity
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.