Using a special camera to take pictures of oral cancers before surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to capture images of oral lesions using reflectance confocal microscopy prior to surgery for patients diagnosed with squamous cell carcinoma of the oral cavity. The images obtained will be compared to traditional biopsy results to evaluate the effectiveness of this imaging technology. The goal is to determine if this method can assist in the early diagnosis of oral cancers and improve surgical guidance. By utilizing a laser-based imaging technique, researchers hope to enhance the understanding of tissue structure in real-time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with biopsy-proven oral SCC who are scheduled to undergo surgery in the MSK Head and Neck Service.
* Ability to sign informed consent.
* Age ≥ 18 years.

Exclusion Criteria:

* Cancer located on a site that may not be convenient or accessible for imaging with the current version of the RCM device (gingivobuccal region, back of the oral cavity, back of the tongue, floor of the mouth, deep under the tongue, etc.).
* Inability to give informed consent.

Where it's running

• Memorial Sloan Kettering Basking Ridge (consent only)
  Basking Ridge, New Jersey, United States Recruiting
• Memorial Sloan Kettering Monmouth (consent only)
  Middletown, New Jersey, United States Recruiting
• Memorial Sloan Kettering West Harrison (consent only)
  Harrison, New York, United States Recruiting
• Memorial Sloan Kettering Cancer Center
  New York, New York, United States Recruiting
• Memorial Sloan Kettering Nassau (consent only)
  Uniondale, New York, United States Recruiting

Study contacts

• Principal investigator: Snehal Patel, MD — Memorial Sloan Kettering Cancer Center
• Study coordinator: Snehal Patel, MD
• Phone: 212-639-3412

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.