Using a special bone graft for sinus floor elevation in dental procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of biphasic calcium sulfate (BCS) as a graft material in sinus floor elevation (SFE) surgery, which is performed to restore bone height in the maxillary region for dental implants. The research aims to assess the success of SFE using BCS, analyze the microarchitecture of the augmented bone over different healing periods, and evaluate the outcomes of dental implants placed in the augmented bone. Patients will undergo preoperative and postoperative imaging to monitor the results. The study focuses on individuals with insufficient bone height due to sinus pneumatization.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over the age of 18 years,
* Patients who need dental implant-borne prostheses,
* Patients with insufficient bone height in the posterior maxilla due to sinus pneumatization.

Exclusion criteria:

.• Patients who had major systemic diseases as classified by the American Society of Anesthesiologists (ASA grades III-IV),

* psychiatric contraindications,
* patients on medication interfering with bone metabolism, including steroid therapy and antiresorptive medication,
* radiation to the head or neck region within the previous five years,
* localized periapical disease, odontogenic and nonodontogenic cysts, and maxillary sinusitis,
* evidence of uncontrolled periodontal disease,
* Alcohol Use Disorder defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5),
* recreational drug abuse,
* heavy smoking (\>10 cigarettes/day),
* diseases of the oral mucosa, including blisters and ulcers, i.e.: red and white lesions, pigmented lesions, benign tumors of the oral cavity, and oral cancer. Leukoplakia, Erythroplakia, Precancerous lesions, Oral squamous cell carcinoma and malign tumors of the soft and hard tissues, Oral candidiasis, Oral lichen planus, Psoriasis, Pemphigus, and Pemphigoid.
* pregnancy or nursing,
* poor oral hygiene

Where it's running

• Semmelweis University Department of Public Dental Health
  Budapest, Budapest, Hungary Recruiting

Study contacts

• Principal investigator: Márton Kivovics, DMD,MSD,PHD — Department of Public Dental Health, Semmelweis University
• Study coordinator: Márton Kivovics, DMD,MSD,PHD
• Email: kivovics.marton@semmelweis.hu
• Phone: 003614591500

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.