Using a smartphone app to improve HPV vaccination rates

Conversational Agents to Improve HPV Vaccine Acceptance in Primary Care

Not applicable Interventional Tufts Medical Center · NCT06367699

This study is testing a smartphone app that helps parents and teens feel more comfortable about getting the HPV vaccine to see if it can increase vaccination rates.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1750 (estimated)
Ages8 Years to 12 Years
SexAll
SponsorTufts Medical Center Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT06367699 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of an animated smartphone application designed to enhance HPV vaccination acceptance among parents and adolescents. The app, known as ECA-HPV, simulates face-to-face conversations to provide vaccine recommendations and motivational support. Participants will complete surveys over a 16-month period to assess their satisfaction with the app and its impact on vaccination rates. The study will compare different versions of the app to determine which features are most effective in promoting vaccination.

Who should consider this trial

Good fit: Ideal candidates include English-speaking parents or guardians of adolescents aged 9-12 who have received one or no doses of the HPV vaccine and have access to a smartphone.

Not a fit: Patients who do not speak English fluently or those who are outside the specified age range for adolescents may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly increase HPV vaccination rates, leading to better cancer prevention outcomes.

How similar studies have performed: Other studies have shown promise in using technology to improve vaccination rates, suggesting that this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

For parent/guardian participants:

1. Speaks English fluently
2. Able to independently consent
3. Has adequate corrected vision to use the ECA-HPV system (based on their ability to go through the consent form)
4. Has adequate hearing to use the ECA-HPV system (based on their ability to hear the research staff member conducting the consent process)
5. Has a smartphone that is able to support the ECA-HPV app

For adolescent participants:

1. Is between the ages of 9-12 at the time of the index (first) well child visit
2. Has received either 1 or none of the HPV vaccine series
3. Speaks English fluently
4. Able to independently assent
5. Has adequate corrected vision to use the ECA-HPV system
6. Has adequate hearing to use the ECA-HPV system
7. Has a smartphone or has access to parent/guardian's smartphone (that is able to support the ECA-HPV app)
8. Has an upcoming well child visit at Boston Medical Center

Exclusion Criteria (for all participants):

1. Is not able to use the ECA-HPV system
2. Has already participated in the study before

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Human Papilloma VirusCancer PreventionVaccination PromotionVaccination AttitudesVaccination Completion
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.