Using a robotic device for precise tumor biopsies during brain surgery
Application of the Autoguide® Positioning Device for Multiple Stereotactic Tumor Biopsies During a Brain Tumor Resection
This study tests whether using a robotic device can help doctors take more accurate tissue samples from brain tumors during surgery to improve treatment outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Medical University of Graz Academic / other |
| Locations | 1 site (Graz, Styria) |
| Trial ID | NCT06306118 on ClinicalTrials.gov |
What this trial studies
This clinical study aims to improve the accuracy of multiple stereotactic tumor biopsies taken during planned resections of glial brain tumors. By utilizing the AutoGuide® robotic positioning device, the study seeks to obtain tissue samples from specific tumor locations before the actual resection, minimizing the risk of undergrading and ensuring that samples remain viable for further treatment. The study addresses the challenges of brain shift and tissue alteration that can occur during surgery, which may lead to inaccurate biopsies and complications. The approach combines preoperative imaging data with intraoperative navigation to enhance precision in tissue sampling.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18-80 with a diagnosed cerebral lesion requiring surgical resection.
Not a fit: Patients who are pregnant, breastfeeding, or unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate tumor biopsies, improving treatment outcomes for patients with brain tumors.
How similar studies have performed: Other studies have shown success with robotic-assisted biopsy techniques, indicating potential for improved outcomes in similar approaches.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-80 years * Diagnosis of a cerebral lesion with the indication for surgical resection * Written informed consent to participate in the present study * MRI and CT scanner compatibility Exclusion Criteria: * Pregnancy, breast feeding * Patients not able to reason * Age \<18 or \>80 years * Claustrophobia
Where this trial is running
Graz, Styria
- Medical University of Graz — Graz, Styria, Austria (Recruiting)
Study contacts
- Principal investigator: Stefan Wolfsberger, Prof. — Medical University of Graz
- Study coordinator: Alexander SG Micko, MD, PhD
- Email: alexander.micko@medunigraz.at
- Phone: +43031638581257
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.