Using a retrograde approach for treating lower limb arterial disease

Retrograde Approach in Ambulatory Practice

Observational Fondation Hôpital Saint-Joseph · NCT04954079

This study is testing a new way to treat lower limb artery disease to see if a special technique helps patients feel better and get the blood flow they need.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorFondation Hôpital Saint-Joseph Academic / other
Locations2 sites (Brest and 1 other locations)
Trial IDNCT04954079 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with obliterative arterial disease of the lower limbs, a condition affecting millions worldwide. It aims to evaluate the effectiveness of a retrograde arterial puncture technique in managing symptomatic patients who require revascularization. The study will include patients aged 18 and older who are experiencing varying degrees of symptoms as classified by the Rutherford classification. The research will be conducted in French-speaking hospitals in Brest and Paris.

Who should consider this trial

Good fit: Ideal candidates are French-speaking adults aged 18 and older with symptomatic obliterative arterial disease requiring revascularization.

Not a fit: Patients who are under guardianship, deprived of liberty, or under court protection will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could improve treatment outcomes and quality of life for patients suffering from lower limb arterial disease.

How similar studies have performed: While this approach is gaining traction, the specific retrograde technique in ambulatory practice is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with age ≥ 18 years
* Patient with symptomatic AOMI (Rutherford 2 to 6) with indication for revascularization
* Patient with ambulatory management
* Patient whose management requires retrograde arterial puncture
* Francophone patient
* Patient who does not object to the use of his/her data for this research

Exclusion Criteria:

* Patient under guardianship or curatorship
* Patient deprived of liberty
* Patient under court protection

Where this trial is running

Brest and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obliterative Arterial Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.