Using a removable titanium clip to treat acute gastric variceal bleeding

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of a removable titanium clip to control acute bleeding from gastric varices. The clip is applied to block the bleeding vessels, allowing for rapid hemostasis, and is removed after five days to prevent complications with future imaging or treatments. This method serves as a temporary solution when other emergency treatments are not feasible, potentially stabilizing patients until further interventions can be performed. The study aims to evaluate the effectiveness and safety of this innovative approach in managing a critical condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The patient and their family agree to and sign the relevant informed consent form.
2. Diagnosed with cirrhosis based on clinical manifestations, laboratory tests, imaging findings, or pathological examinations.
3. History of symptoms related to variceal upper gastrointestinal bleeding, such as hematemesis, melena, or rectal bleeding.
4. Patients confirmed by endoscopy to have bleeding from ruptured gastric varices.
5. Patients who are hemodynamically stable before or after initial fluid resuscitation.
6. Aged 18 to 75 years.

Exclusion Criteria:

1. Those with concomitant bleeding from ruptured esophageal varices.
2. A history of gastrointestinal-related surgical procedures.
3. Individuals with altered consciousness who are difficult to treat.
4. Those with concomitant malignant tumors.
5. Individuals with serious diseases involving the heart, brain, lungs, or kidneys.
6. Pregnant and breastfeeding women.
7. Those with contraindications to relevant treatments.

Where it's running

• Removable Titanium Clip
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Changqing Sun
• Email: 18851675250@163.com
• Phone: 18851675250

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.