Using a pancreatic stent to reduce pancreatitis risk after a specific procedure
Official title: Does Pancreatic Stent Decrease the Risk of Pancreatitis After Pancreatic Sphincterotomy for Difficult Cannulation?
Run by Helsinki University Central Hospital · NCT04408482 · Data updated 2026-11-12
This study tests if putting a stent in the pancreas can help prevent pancreatitis in patients who have a tough time with a certain procedure called ERCP.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 268 (estimated) |
| Sponsor | Helsinki University Central Hospital Academic / other |
| Locations | 1 site (Helsinki) |
| Status | Recruiting |
| Started | August 1, 2020 |
| Main results expected | September 1, 2028 |
| Study ends | September 1, 2028 |
| Registry record updated | March 3, 2026 |
| Trial ID | NCT04408482 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults presenting with naïve papilla requiring ERCP for common bile duct cannulation.
✕Probably not a fit
Patients under 18 years old, those with acute pancreatitis, or those who do not consent to the study may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate whether the placement of a prophylactic pancreatic stent can reduce the risk of post-endoscopic pancreatitis after pancreatic sphincterotomy in patients who experience difficult cannulation. It compares outcomes between patients who receive the stent and those who do not. The study focuses on patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) for common bile duct cannulation. The definition of difficult cannulation is based on established literature criteria.
Why it matters
Potential benefit: If successful, this approach could significantly lower the incidence of pancreatitis in patients undergoing ERCP.
How similar studies have gone: Other studies have explored similar interventions, but the specific use of pancreatic stents in this context is less common and may provide novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients with naïve papilla presenting to ERCP with indication of common bile duct (CBD) cannulation will be considered to the study. Exclusion Criteria: * Exclusion criteria are age below 18 years, acute pancreatitis and no consent to the study.
Where it's running
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Helsinki Univeristy Hospital
Helsinki, Finland Recruiting
Study contacts
- Study coordinator: Andrea Tenca, MD, PhD
- Email: ante14@hotmail.it
- Phone: +358408484955
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
HFNC vs Microstream nasal cannula during ERCP
This study compares high-flow nasal oxygen with the Microstream Advance nasal cannula to see which one better keeps patients’ oxygen levels stable during ERCP procedures done under deep sedation.
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Developing a predictive score for complications after ERCP procedures
This study is trying to find out what factors can lead to complications after ERCP procedures to help predict risks for patients undergoing this treatment.
-
Using biodegradable stents to treat bile duct issues in liver transplant patients
This study is testing if biodegradable stents can help liver transplant patients with bile duct problems feel better and avoid complications compared to regular plastic stents.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.