Using a pain relief cocktail for patients having laparoscopic gallbladder surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the safety and effectiveness of a cocktail consisting of ropivacaine, sodium bicarbonate, and dexamethasone for local infiltration analgesia in patients undergoing ambulatory laparoscopic cholecystectomy. Researchers will compare this cocktail to ropivacaine alone to determine if it reduces moderate to severe pain during movement in the first six hours post-surgery. Participants will receive the treatment at the end of their surgery and report their pain levels at various intervals using a Numeric Rating Scale. The study is conducted at Sichuan Provincial People's Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing daytime laparoscopic cholecystectomy in Sichuan Provincial People's hospital ② Age: 18-70 years

  * American society of Anesthesiologists physical status classification system I-II ④ 18 kg/㎡≤ BMI ≤ 30 kg/㎡ ⑤ No communication barriers, able to understand the research process and the use of pain scale.

    * Signed informed consent

Exclusion Criteria:

* Drug allergy related to this study

  * History of chronic pain, long-term use of analgesic drugs (equivalent to ≥ 10mg oxycodone per day), alcohol abuse, gastrointestinal bleeding or perforation after application of non steroidal anti-inflammatory drugs

    * Patients with ischemic heart disease, peripheral arterial vascular or cerebrovascular disease, or patients with pulmonary heart disease, active peptic ulcer or gastrointestinal bleeding, or patients with inflammatory bowel disease

      * Patients taking monoamine oxidase inhibitors or within 2 weeks after discontinuation ⑤ Preoperative pain score (NRS ) was greater than or equal to 4 points ⑥ Participated in other clinical studies within three months

Where it's running

• Sichuan Provincial People's Hospital
  Chengdu, Sichuan, China Recruiting

Study contacts

• Principal investigator: Dan Fan, M.D/PhD — Sichuan Provincial People's Hospital
• Study coordinator: Yue Liu
• Email: 364876168@qq.com
• Phone: 86-18980704707

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Single-level vs two-level erector spinae plane block for breast surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.