Using a new technique to repair large paraesophageal hernias

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the use of a novel surgical technique called posterior rectus sheath flap hiatal augmentation (PoRSHA) for repairing challenging paraesophageal hernias in older patients. The approach utilizes the patient's own vascularized tissue to enhance the repair of the diaphragmatic hiatus, aiming to improve outcomes and durability compared to traditional methods. The study will observe patients undergoing this procedure to evaluate its effectiveness and safety in addressing large and recurrent hernias. The hypothesis is that PoRSHA can provide a stronger and more reliable repair than synthetic mesh or primary closure techniques.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients undergoing PoRSHA. PoRSHA will be offered to all patients with PEH defects measuring greater than 4 cm.

Exclusion Criteria:

* Patients that did not have PoRSHA.
* Patients requiring therapeutic anticoagulation perioperatively or those with bleeding disorders, considering the added risk of bleeding at the donor site with exposed rectus muscle.

Where it's running

• The University of Chicago
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Yalini Vigneswaran, MD, MPH — University of Chicago
• Study coordinator: Yalini Vigneswaran
• Email: yvigneswaran@bsd.uchicago.edu
• Phone: 773-702-6337

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Removing the hernia sac to lower crural tension during paraesophageal hernia repair

  This study will test whether taking out the hernia sac during paraesophageal hernia surgery lowers tension on the diaphragmatic crura in adults having repair for symptomatic paraesophageal hernia.

  Recruiting Corewell Health West · Grand Rapids, Michigan · NCT07197619

• Comparing two surgical methods for hiatal hernia repair

  This study is testing which of two surgical methods for fixing hiatal hernias works better to prevent them from coming back and improve quality of life for patients.

  Recruiting Kuopio University Hospital · Kuopio · NCT06725433

• Repairing large hiatal hernias using Ovitex mesh

  This study is testing if a special mesh can help fix large hiatal hernias and see if it keeps them from coming back while also checking how safe it is for patients.

  Recruiting Foregut Research Foundation · Lone Tree, Colorado · NCT06193551

• Comparing mesh and sutures for paraesophageal hernia repair

  This study is testing whether using a special mesh or stitches works better to prevent paraesophageal hernias from coming back after surgery for people who need this repair.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05974722

• Comparing sutures and polyglactin mesh for hiatal hernia repair

  This study is testing whether using mesh instead of just stitches during surgery can help prevent paraesophageal hernias from coming back in patients.

  Recruiting Oulu University Hospital · Oulu · NCT05201508

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.