Using a new gel to prevent adhesions after first-trimester miscarriage treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a new cross-linked hyaluronan gel in preventing intrauterine adhesions (IUA) following surgical evacuation for first-trimester miscarriage. The study is a prospective, randomized controlled trial that compares the incidence of IUA in patients treated with the gel versus a control group. It also assesses the severity of adhesions, rates of complications, and subsequent reproductive outcomes. The trial aims to provide more data on the gel's efficacy in this specific patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women 18 years old or above
* No previous history of IUA/ Asherman's syndrome
* No previous surgical history of EVA or dilatation or curettage or surgical termination of pregnancy or caesarean section
* No previous history of therapeutic hysteroscopic surgeries
* Voluntary informed consent and understanding of study

Exclusion Criteria:

* previous therapeutic hysteroscopic procedures (e.g. endometrial ablation, removal of fibroids or polyps, surgical correction of congenital uterine anomalies or adhesiolysis)
* suspicion of molar pregnancy
* genital tract malformation
* suspicion of active infection or genital tract malignancy or genital tuberculosis
* abnormal blood coagulation
* inability to tolerate pelvic examination known
* suspected intolerance of hypersensitivity to NCH gel or its derivatives
* patient refusal

Where it's running

• The Chinese University of Hong Kong
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Elaine NG
• Email: elaineng@cuhk.edu.hk
• Phone: 35052745

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.