Using a new device to treat Candy Cane Syndrome
Official title: Evaluation of the Performance of MAgnetic Gastrointestinal Universal Septotome for Treatment of Candy Cane Syndrome
Run by Erasme University Hospital · NCT05938439 · Data updated 2026-11-12
This study is testing a new device to see if it can help people with Candy Cane Syndrome feel better by relieving their symptoms without needing major surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 51 (estimated) |
| Sponsor | Erasme University Hospital Academic / other |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | August 1, 2023 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | November 18, 2023 |
| Trial ID | NCT05938439 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with Candy Cane Syndrome who experience at least one associated symptom such as pain, nausea, or vomiting.
✕Probably not a fit
Patients with certain conditions such as refractory stenosis, coagulation disorders, or those who have undergone recent abdominal surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of the MAgnetic Gastrointestinal Universal Septotome (MAGUS) for treating Candy Cane Syndrome, a complication that can arise after gastric surgery. The device is implanted endoscopically and aims to alleviate symptoms by creating a passage in the affected blind loop of the intestine. The study focuses on patients experiencing symptoms such as pain, nausea, and vomiting, which are associated with this condition. The goal is to provide a less invasive alternative to traditional surgical revision methods.
Why it matters
Potential benefit: If successful, this approach could offer a less invasive treatment option for patients suffering from Candy Cane Syndrome, potentially improving their quality of life.
How similar studies have gone: Previous studies using similar endoscopic techniques have shown promise, but this specific approach with the MAGUS device is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient is diagnosed with candy cane syndrome based on clinical and endoscopic and/or radiologic assessment * Patient has at least one of this 3 symptoms associated to CCS: pain, nausea, vomiting, regurgitation * Patient agrees and is able to comply with the study procedures and provide written informed consent to participate in the study Exclusion Criteria: * Refractory stenosis of the UGI proximal to the septum * Septum height smaller than 2 cm or higher than 8 cm * Coagulation disorders. • Previous implantation of a magnetic-sensitive medical device (including active electronic implant, metallic stent, …). * Dysphagia related to motility disorder * Planned MRI in the following month (30 days) of intervention * Condition that could compromise patient safety * Patient who went through an abdominal surgery less than 8 weeks before implantation of the magnets * Patient pregnant, breastfeeding or incapacitated * Patient currently enrolled in another clinical trial
Where it's running
-
Hôpital Universitaire de Bruxelles - Hôpital Erasme
Brussels, Belgium Recruiting
Study contacts
- Study coordinator: Pauline Van Ouytsel
- Email: pauline.vanouytsel@hubruxelles.be
- Phone: 025556531
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Two-step Propofol Dose for Induction to See If It Reduces Injection Pain
This study tests whether starting with a small propofol dose and then giving the rest can lessen the pain patients feel from propofol injections.
-
Neutral fluid balance in adults with traumatic brain injury (LIMIT-TBI)
This study tests whether keeping daily fluid balance around zero (within 500 mL) for the first 5 days in the ICU is feasible and safe for adults with traumatic brain injury.
-
Dexmedetomidine conscious sedation to protect breathing and blood pressure during TAVI
This trial will test whether dexmedetomidine used for conscious sedation during transfemoral TAVI helps reduce breathing problems and unstable blood pressure in patients aged 60 and over.
-
How short high-oxygen exposures affect brain blood flow during mechanical ventilation
We will test whether brief, controlled increases in ventilator oxygen change brain blood flow in adults who are intubated and on mechanical ventilation in the ICU.
-
Comparing two methods for frozen embryo transfer in women with regular cycles
This study is testing a new way to transfer frozen embryos in women with regular cycles to see if it works just as well as the current method while allowing for better planning.
-
Understanding brain blood flow and metabolism in patients with brain lesions
This study is trying to understand how blood flow and metabolism in the brain are affected in patients with brain tumors like glioblastoma, glioma, and astrocytoma.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.