Using a new bipolar knife for removing esophageal lesions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the efficacy, safety, and feasibility of a novel bipolar-current endoscopic submucosal dissection (ESD) device for the removal of esophageal lesions. Conducted at Baylor St Luke's Medical Center and Mayo Scottsdale, the research aims to improve upon traditional monopolar knives that can cause complications such as post coagulation syndrome and esophageal strictures. The ESD technique is minimally invasive, allowing for the removal of high-risk esophageal polyps without the need for more invasive surgical procedures. The study will prospectively assess outcomes in patients referred for resection of precancerous lesions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient is \>18 years of age
* Patient can provide informed consent
* Patient is referred for resection of precancerous lesions meeting the following criteria:

  * Mucosal based polyp
  * Located gastroesophageal junction (GEJ) or proximal to GEJ
  * No previous endoscopic resection attempted (EMR or ESD)

Exclusion Criteria:

* Patients with International Normalized Ratio (INR) \>1.5 or Platelets \<50,000
* Lesions extending past GEJ
* Subepithelial lesions

Where it's running

• Baylor College of Medicine
  Houston, Texas, United States Recruiting

Study contacts

• Study coordinator: Salmaan A Jawaid, MD
• Email: Salmaan.Jawaid@bcm.edu
• Phone: 7137980950

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.