Using a nerve block to manage pain and swelling in jaw surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of sphenopalatine ganglion (SPG) block in controlling intraoperative pain and reducing postoperative swelling in adults undergoing bimaxillary orthognathic surgery. Participants aged 18 to 45 will be randomly assigned to receive either an SPG block or a sham block before their surgery. The study aims to compare pain levels, opioid use, and swelling between the two groups over a one-month postoperative period. By assessing these outcomes, researchers hope to determine if the SPG block can improve recovery and reduce complications associated with the surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with bimaxillary orthognathic surgery indication
* Patients with American Society of Anesthesiologistsscores (ASA) I-II
* Patients between the ages of 18-45

Exclusion Criteria:

* Patients with local anesthetic allergy
* Patients undergoing genioplasty
* Syndromes associated with secondary deformities in addition to jaw deformities
* Patients with a history of jaw surgery
* Patients with uncontrolled hypertension
* Patients with a history of substance abuse
* Patients with chronic pain lasting more than 3 months
* Patients using analgesic and hypnotic agents for more than 2 weeks
* Recent situations that may cause facial edema (tooth extraction, facial trauma, etc.)
* Patients with psychiatric disorders
* Patients with diabetes mellitus
* Patients with bleeding disorders

Where it's running

• Bezmialem Vakıf Üniversitesi
  Istanbul, Fatih, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Büşra Ceylan, Resident Doctor — Bezmialem Vakıf Üniversitesi
• Study coordinator: Büşra Ceylan, Resident Doctor
• Email: bcalis@bezmialem.edu.tr
• Phone: +905058945208

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.