Using a mouth guard to help prevent sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a Mandibular Advancement Appliance (MAA) in patients with Obstructive Sleep Apnea (OSA) and whether additional support interventions can increase its usage compared to standard care. Participants aged 40 and older with a confirmed diagnosis of OSA will be randomly assigned to either an intervention group, receiving extra support and education, or a control group receiving standard care. The study will also explore factors influencing patients' adherence to using the MAA, including psychological and social aspects. Data on usage will be collected through sleep diaries and sensors in the appliance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (≥ 40 years old)
* Confirmed diagnosis of OSA (AHI ≥ 5)
* Referred for MAA therapy
* Must be able to understand, read and write English; with the assistance of a translator

Exclusion Criteria:

* Insufficient teeth for MAA fabrication
* Poor dental and/or periodontal health
* Symptomatic Temporomandibular Disorder (TMD)
* Previously used an MAA
* Patients with Epilepsy

Where it's running

• Royal London Dental Hospital
  London, United Kingdom Recruiting

Study contacts

• Study coordinator: Ama Johal
• Email: a.s.johal@qmul.ac.uk
• Phone: 0207 377 7686

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.