Using a laser to tighten facial skin
Efficacy and Safety of Fractional 1064-nm Picosecond Laser for Facial Skin Tightening
This study is testing whether a special laser treatment can help tighten facial skin for people aged 40 to 55 who have some sagging.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 40 Years to 55 Years |
| Sex | All |
| Sponsor | Mahidol University Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT06231914 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the efficacy and safety of a fractional 1064-nm picosecond laser for tightening facial skin in individuals aged 40 to 55 with mild to moderate laxity. Participants will undergo three treatment sessions spaced four weeks apart, with follow-up assessments at one, three, and six months post-treatment. The study aims to measure changes in skin texture, elasticity, and laxity, as well as monitor any adverse events associated with the treatment.
Who should consider this trial
Good fit: Ideal candidates are Asian individuals aged 40 to 55 years with a BMI under 25 and mild to moderate facial skin laxity.
Not a fit: Patients who are pregnant, have active skin infections, or have a history of hypertrophic scars or keloids may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a non-invasive option for improving facial skin laxity and overall appearance.
How similar studies have performed: Previous studies using similar laser technologies have shown promising results in skin tightening, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 40-55 years * BMI \< 25 kg/m2 * Asian * Mild to moderate facial skin laxity using quantitative grading scale (grade 1.5-2.5) Exclusion Criteria: * Pregnant or lactation * Subjects who have been treated with any kind of energy-based device 6 months prior to the inclusion * Subjects who have been injected with botulinum toxin, filler, or platelet-rich plasma on their faces 6 months prior to the inclusion * Active skin infections * History of hypertrophic scars or keloids
Where this trial is running
Bangkok
- Department of Dermatology, Siriraj Hospital, Mahidol University — Bangkok, Thailand (Recruiting)
Study contacts
- Principal investigator: Woraphong Manuskiatti, MD — Mahidol University
- Study coordinator: Woraphong Manuskiatti, MD
- Email: doctorlaser@gmail.com
- Phone: 6624194333
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.