Using a continuous nerve block to manage pain after knee surgery
Continuous Adductor Canal Block in Fast Track Total Knee Arthroplasty
This study is testing if a continuous nerve block can help people manage pain better after knee surgery and reduce the need for opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Samuel Lunenfeld Research Institute, Mount Sinai Hospital Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT05962970 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of a continuous adductor canal block (CACB) in patients undergoing fast track total knee arthroplasty (TKA). The approach involves the use of a perineural catheter to deliver local anesthetic, aiming to enhance pain management and reduce opioid consumption post-surgery. The study will measure patient-reported quality of recovery and assess the rate of readmissions. Investigators hypothesize that CACB will lead to improved outcomes compared to traditional pain management methods.
Who should consider this trial
Good fit: Ideal candidates are adults over 21 undergoing unilateral primary TKA in a fast track setting with no history of drug dependency.
Not a fit: Patients with chronic opioid use, coagulopathy, or contraindications to catheter placement may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid use and improve recovery quality for patients undergoing knee surgery.
How similar studies have performed: While there are no published prospective randomized controlled trials specifically assessing CACB in same-day primary knee arthroplasties, the approach shows promise based on existing literature.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing unilateral primary TKA in the fast track setting. * Patients older than 21 years of age, with American Society of Anesthesiologists (ASA) * Physical status I-III * No alcohol or drug dependency * Sufficient understand and co-operation about the perineural catheter. Exclusion Criteria: * Perioperative complication or discharge delay leading to hospital admission. * Chronic opioid use of morphine 30mg equivalent per day for last 2 consecutive weeks. * Allergy to the study medications; * Coagulopathy and platelet count \< 105/μL; * Patients with contraindications to the insertion of an epidural or adductor canal catheter (severe anatomic abnormalities or history of previous surgery at the site of catheter placement).
Where this trial is running
Toronto, Ontario
- Mount Sinai Hospital, Toronto — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Naveed Siddiqui, MD — Associate Professor
- Study coordinator: Naveed Siddiqui, MD
- Email: naveed.siddiqui@uhn.ca
- Phone: 416-586-4800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.