Using a collagen membrane to help the gum behind the second molar heal after removing an impacted lower wisdom tooth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study places a new-generation collagen membrane at the distal aspect of the second molar when removing mesioangular or horizontally impacted mandibular third molars in adults 25 years and older. Patients with symmetrical bilateral impactions are enrolled so treated sites can be compared with the opposite side within the same patient. Clinical and radiographic measures of distal periodontal healing will be followed over time to determine whether the membrane improves tissue and bone recovery. Participants are excluded for bleeding or immune disorders, relevant allergies, or pregnancy, and all must provide informed consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 25 years or older.
* Patients with mesioangular or horizontally impacted mandibular third molars. The highest point of mandibular third molars are lower than the occlusal surface of adjacent second molars (classified B, C according to Pell - Gregory's category).
* Patients with symmetrical lower third molars on both sides with same classification according to Pell - Gregory's category. The difference of third molars inclination on both side is not more than 15°.
* Patients with lower second molars on both sides have no cavities or fillings that affect the determination of the cemento-enamel junction.
* Patients are explained, counseled clearly and sign their consent to participate in the study.

Exclusion Criteria:

* Patients with coagulation or immune disorders.
* Patients allergic to local anesthetics (Lidocaine 2% with Adrenaline 1:100,000) or any drugs used in the study.
* Patients allergic to products or food derived from pigs.
* Pregnant or breastfeeding patients.
* Patients who smoke.
* Patients with systemic conditions that contraindicate surgical procedures.
* Patients with clinical or radiographic signs suggestive of tumors (benign or malignant) associated with or in proximity to the mandibular third molar.
* Patients with missing mandibular second molars.

Where it's running

• University of Medicine and Pharmacy at Ho Chi Minh city
  Ho Chi Minh City, Vietnam Recruiting

Study contacts

• Study coordinator: Phong Cu Lam, MD.DDS
• Email: lamcuphong@ump.edu.vn
• Phone: +84932114888

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.