Using a carvacrol gel to reduce pain after gum graft surgery

Clinical Evaluation of Carvacrol Loaded Absorbable Gelatin Sponge As a Palatal Bandage After Free Gingival Graft Harvesting : a Randomized Clinical Trial

Not applicable Interventional British University In Egypt · NCT06806566

This study is testing if a special gel can help reduce pain after gum graft surgery for people with certain gum issues.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorBritish University In Egypt Academic / other
Locations1 site (Cairo)
Trial IDNCT06806566 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a carvacrol-loaded absorbable gelatin sponge as a palatal dressing following the harvesting of free gingival grafts. The study aims to determine if this treatment can reduce post-operative pain at the donor site in patients undergoing gum graft procedures. Participants will be randomly assigned to receive either the carvacrol gel or a control treatment, and their pain levels will be assessed post-surgery. The trial focuses on patients with specific mucogingival defects and good oral hygiene.

Who should consider this trial

Good fit: Ideal candidates are patients with mucogingival defects scheduled for free gingival grafts who maintain good oral hygiene.

Not a fit: Patients who are smokers, pregnant, or have medical conditions that compromise their health may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce post-operative pain for patients undergoing gum graft surgeries.

How similar studies have performed: There is limited information on similar studies, making this approach relatively novel in the context of palatal wound management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1 - Patients with mucogingival defects scheduled for free gingival graft. 2- Medically free patients 3- Palate with sufficient connective tissue to accommodate soft tissue defects. 4- Good oral hygiene

Exclusion Criteria:

1 - Smokers 2- Pregnancy 3- Medically compromised patients 4- Severe gag reflex 5- Patients allergic to the used agent 6- Occlusal trauma at the site of graft

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Palatal Wound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.