Using a carbohydrate solution before surgery to improve recovery
The Effect of A Newly Formulated Preoperative Oral Carbohydrate Solution on Gastric Emptying, Postoperative Nausea and Vomiting and Stress Response
This study tests if drinking a special carbohydrate solution before surgery can help patients recover better and feel less anxious compared to those who fast or just drink water.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Bezmialem Vakif University Academic / other |
| Locations | 1 site (Istanbul, Fatih) |
| Trial ID | NCT06289543 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a low osmolality oral carbohydrate solution on gastric emptying, preoperative anxiety, and postoperative outcomes in patients undergoing elective laparoscopic cholecystectomy. Participants are divided into three groups: one fasting, one drinking water, and one consuming the carbohydrate solution two hours before surgery. The study aims to evaluate gastric volume, anxiety levels, stress responses, insulin resistance, and nausea and vomiting post-surgery. The goal is to enhance patient comfort and recovery by minimizing fasting time and its associated negative effects.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 scheduled for elective laparoscopic cholecystectomy with ASA physical status I-II.
Not a fit: Patients with gastrointestinal disorders, high BMI, or significant medical history may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved recovery experiences and outcomes for surgical patients.
How similar studies have performed: Other studies have shown positive outcomes with preoperative carbohydrate solutions, suggesting this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 18-65 * Elective laparoscopic cholecystectomy planned under general anesthesia * American Society of Anesthesiologists (ASA) class I-II physical condition Exclusion Criteria: Patients with gastroesophageal reflux and gastrointestinal motility disorders diabetes mellitus Mental retardation, previous neurological disease symptoms (syncope, dementia, Alzheimer, etc.) Chronic alcoholism Difficult Intubation Patients with ASA physical status classes ≥III Patients with a body mass index of 35 and above History of Meniere and motion sickness Presence of previous history of postoperative nausea and vomiting Smoking
Where this trial is running
Istanbul, Fatih
- Bezmialem University — Istanbul, Fatih, Turkey (Recruiting)
Study contacts
- Study coordinator: Emine Seyda Teloglu
- Email: eteloglu@bezmialem.edu.tr
- Phone: +905394191544
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.