Using a brief swallowing test to detect vocal cord paralysis after major lung surgery
Official title: Predictive Value of a Preliminary Swallowing Test Compared to Postoperative Nasofibroscopy to Identify Vocal Cord Paralysis After Pulmonary Resection
Run by University Hospital, Rouen · NCT05193240 · Data updated 2026-11-12
This trial will test whether a quick swallowing test performed by a physiotherapist can find vocal cord paralysis in adults after major lung resection for lung cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 72 (estimated) |
| Sponsor | University Hospital, Rouen Academic / other |
| Locations | 1 site (Rouen) |
| Status | Recruiting |
| Started | September 11, 2024 |
| Main results expected | May 2026 |
| Study ends | May 2026 |
| Registry record updated | February 17, 2026 |
| Trial ID | NCT05193240 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) scheduled for major left lung resection or right lung resection with upper lymph node dissection for lung cancer who can read, consent, and are not pregnant or breastfeeding are ideal candidates.
✕Probably not a fit
Patients with prior swallowing disorders, known neurological impairments, preoperative nasogastric feeding, or those unable to consent are unlikely to benefit from this screening approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will compare a physiotherapist‑administered preliminary bedside swallowing test performed after surgery with the standard postoperative nasofibroscopy to identify ipsilateral vocal cord paresis or paralysis. The study enrolls adults undergoing major left lung resection or right lung resection with upper lymph node dissection for lung cancer. Patients with preexisting swallowing disorders, neurological sequelae, or preoperative nasogastric feeding are excluded. The goal is to determine whether the simpler bedside test can reliably flag patients at risk of aspiration and other complications so that targeted ENT evaluation and management can follow.
Why it matters
Potential benefit: If successful, the bedside swallowing test could enable earlier detection of vocal cord paralysis after lung surgery and help prevent aspiration, feeding problems, and longer hospital stays.
How similar studies have gone: Bedside swallowing tests have shown mixed but often promising results in other surgical and neurological settings, while their specific use to predict vocal cord palsy after lung resection is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult (≥ 18 years old) * Patient who is scheduled for a major left lung resection surgery (segmentectomy, lobectomy, pneumonectomy) or a right lung resection with upper lymph node dissection in the context of lung cancer * Patient who capable to read and understand the patient information and consent. * Patient capable to read and sign the consent form * Patient with social insurance * Woman of childbearing age with effective contraception (see WHO definition), postmenopausal woman (≥ 12 months of amenorrhea not induced by therapy) * Negative urine pregnancy test Exclusion Criteria: * History of swallowing or eating disorders, * Neurological history with known sequelae or cognitive disorders * Preoperative nasogastric tube feeding * Person deprived of liberty by an administrative or judicial decision or person placed under judicial protection, under guardianship or curatorship, * Pregnant or breastfeeding woman * Patient participating in another clinical trial with the same primary outcome
Where it's running
-
Rouen University Hospital
Rouen, France Recruiting
Study contacts
- Principal investigator: Baptiste MICHAUX, physiotherapist — University Hospital, Rouen
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.