Using a bone graft to prevent ridge loss after removing multiple teeth

Biomaterial to Counteract Ridge Reduction Following the Removal of Multiple Adjacent Teeth. A Prospective Randomized Controlled Study.

Not applicable Interventional Institute Franci · NCT02903667

This study is testing whether using special bone graft materials can help people who have lost multiple teeth keep their jawbone from shrinking and make it easier to place dental implants later on.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages25 Years and up
SexAll
SponsorInstitute Franci Academic / other
Locations1 site (Padova)
Trial IDNCT02903667 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of using Bio-Oss Collagen and Bio-Gide to counteract bone loss following the extraction of multiple adjacent teeth. It is a multicenter, randomized trial that aims to evaluate the effectiveness of these materials in maintaining ridge dimensions and facilitating implant placement after six months of healing. The study will enroll 40 participants who require two or more implants due to the removal of adjacent teeth, measuring ridge changes and bone loss over time. The goal is to provide insights into optimal grafting techniques for improved dental outcomes.

Who should consider this trial

Good fit: Ideal candidates are individuals needing two or more implants after the extraction of adjacent teeth with intact extraction sockets.

Not a fit: Patients with uncontrolled systemic diseases, untreated rampant caries, or those unable to comply with follow-up may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve bone preservation and implant success rates for patients undergoing multiple tooth extractions.

How similar studies have performed: While similar studies have explored bone grafting techniques, this specific approach to multiple adjacent extractions is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:intact extraction sockets following removal of the natural teeth defined by:

* a marginal dehiscence defect of any of the facial bone walls of 3 mm
* no facial fenestration present in the apical of the marginal bone crest

Exclusion Criteria:

* untreated rampant caries and uncontrolled periodontal disease
* uncontrolled diabetes or any other systemic or local disease or condition that would compromise post-operative healing
* unable or unwilling to return for follow-up or unlikely to be able to comply with study procedures according to investigators judgement.

Where this trial is running

Padova

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alveolar Ridge TraumaBone Resorptionbone graftingimplantologyoral surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.