Using a 3D culture model to study circulating tumor cells in head and neck cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate circulating tumor cells (CTCs) in patients with head and neck squamous cell carcinoma (HNSCC) using a 3D organoid culture model. The researchers will isolate high-purity CTCs from blood samples using a specialized device and analyze them to gain insights into cancer metastasis and potential biomarkers. The study focuses on understanding the molecular mechanisms behind cancer recurrence and progression, which remain poorly understood. By cultivating nearly 100% viable CTCs, the study seeks to enhance the utility of CTCs in cancer research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. age ≥ 18
2. agree with blood drawing and follow the procedure of the trial

a.health participants:without cancer over 5 yaers b.cancer participants:pathology: metastatic HNSCC patients

Exclusion Criteria:

1. health participants:with serious illness
2. cancer participants:none

Where it's running

• Chang Gung Memorial Hospital
  Taoyuan, Taiwan Recruiting

Study contacts

• Study coordinator: Chia-Hsun Hsieh, PhD
• Email: wisdom5000@gmail.com
• Phone: 0975366137

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.