Using 68Ga-PSMA-617 PET imaging for solid cancers
Official title: Pragmatic Study on the Use of 68Ga-PSMA-617 PET/CT Imaging as a Standard of Care to Influence Clinical Management of Tumors Overexpressing PSMA.
Run by Centre de recherche du Centre hospitalier universitaire de Sherbrooke · NCT05228106 · Data updated 2026-11-12
This study is testing a new type of imaging called 68Ga-PSMA-617 to see if it can help doctors better detect and manage solid tumors that express PSMA, not just prostate cancer.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Centre de recherche du Centre hospitalier universitaire de Sherbrooke Academic / other |
| Locations | 1 site (Sherbrooke, Quebec) |
| Status | Recruiting |
| Started | January 21, 2022 |
| Main results expected | January 31, 2027 |
| Study ends | January 31, 2027 |
| Registry record updated | February 7, 2024 |
| Trial ID | NCT05228106 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with suspected or confirmed solid tumors that express PSMA.
✕Probably not a fit
Patients with non-solid tumors or those who have had a severe allergic reaction to 68Ga-PSMA-617 may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project monitors the safety profile of 68Ga-PSMA-617 PET imaging in patients with PSMA-expressing solid tumors. It is a single-site, pragmatic, non-randomized, and open-label study that includes all solid tumors expressing PSMA, not just prostate cancer. The study aims to integrate this imaging modality into routine care for better detection and management of eligible cancers, while also assessing its impact on patient management compared to current standards.
Why it matters
Potential benefit: If successful, this could enhance the detection and management of various solid tumors, leading to improved patient outcomes.
How similar studies have gone: While the use of 68Ga-PSMA-617 is primarily established for prostate cancer, its application in other solid tumors is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Clinical requisition for a 68Ga-PSMA-617 PET/CT signed by a referring doctor; 2. Patients with suspected, proven or prior tumor expressing PSMA; 3. Informed consent by patient. Exclusion Criteria: 1. Patient refusal to participate; 2. Prior severe anaphylactic reaction to 68Ga-PSMA-617 .
Where it's running
-
Chus
Sherbrooke, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Éric E Turcotte, MD — Université de Sherbrooke, Centre de Recherche du CHUS
- Study coordinator: Stéphanie Dubreuil
- Email: Stephanie.Dubreuil2@usherbrooke.ca
- Phone: 819-346-1110
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.