Using 64Cu-DOTATATE PET imaging for diagnosing Lyme neuroborreliosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of 64Cu-DOTATATE PET/CT/MRI imaging in diagnosing Lyme neuroborreliosis (LNB) in patients who are clinically suspected of having the condition. A total of 50 patients will be included, with comparisons made between those with confirmed LNB through cerebrospinal fluid (CSF) analysis and those without CSF verification. The researchers hypothesize that this imaging technique will enhance diagnostic accuracy and provide prognostic information regarding the risk of persistent symptoms. The ultimate goal is to improve early diagnosis and treatment initiation for better patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age ≥ 18 years AND

* Clinical suspicion of LNB AND
* Must be able to read and understand the patient information and to give informed consent -

Exclusion Criteria:

* Pregnancy OR
* Breast-feeding OR
* Concluded antibiotic treatment OR
* Weight more than the maximum weight limit for the PET/CT/MRI bed of the scanner (140 kg) OR
* History of allergic reaction attributable to compounds of similar chemical or biologic composition to 64Cu-DOTATATE OR
* Contraindications to MR (check list) -

Where it's running

• Anne-Mette Lebech
  Copenhagen, Capital Region, Denmark Recruiting

Study contacts

• Principal investigator: Anne-Mette Lebech — Copenhagen University Hospital, Rigshospitalet
• Study coordinator: Anne-Mette Lebech
• Email: Anne-Mette.lebech@regionh.dk
• Phone: +4535458622

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.