Using 3D technology for personalized nasal reconstruction

Regenerative Medicine Approach to Nasal Reconstruction

Not applicable Interventional Mayo Clinic · NCT05273060

This study is testing if using 3D technology for personalized nasal reconstruction can make surgery safer and more effective for people with nasal defects from cancer, trauma, or previous surgeries.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Phoenix, Arizona)
Trial IDNCT05273060 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the safety and effectiveness of a regenerative medicine approach to nasal reconstruction by comparing traditional surgical planning methods with advanced 3D preoperative scanning, printing, and planning techniques. Patients with nasal defects due to cancer, trauma, or prior surgeries will be involved, and the study will focus on creating individualized cartilage grafts and skin templates using 3D technology. The goal is to improve surgical outcomes, reduce operative times, and enhance the overall patient experience by providing tailored solutions for nasal reconstruction.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 100 who require nasal reconstruction due to various defects.

Not a fit: Patients under 18 years old will not benefit from this study as their cases are managed differently.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and personalized nasal reconstruction procedures for patients.

How similar studies have performed: Other studies have shown promise in using 3D technology for surgical planning, indicating potential success for this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Males or female, age range is ≥ 18 to ≤ 100, based on historical surgical experience.
* Patients undergoing nasal reconstruction.
* Patients will be identified from the Facial Plastic Surgery clinic of the PI.

Exclusion Criteria:

- Patients \< 18 are excluded because these cases are in combination with providers from PCH and patients have shared/limited postoperative follow up as a result.

Where this trial is running

Phoenix, Arizona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nasal Surgical ProceduresRegenerative Medicine
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.