Using 3D printing to treat lower limb bone defects
Multi-center Study on Comprehensive Diagnosis and Treatment of Lower Limb Bone Defect Based on Three-dimensional Printing Technology
Peking University Third Hospital · NCT06269354
This study is testing a new 3D printing method to see if it can help people with lower limb bone defects heal better and get back to normal activities faster after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Peking University Third Hospital (other) |
| Locations | 1 site (Beijing, Haidian) |
| Trial ID | NCT06269354 on ClinicalTrials.gov |
What this trial studies
This study focuses on the diagnosis and treatment of lower limb bone defects using a novel 3D printing technology developed by the Orthopedics Department of Peking University Third Hospital. The TCBridge system allows for personalized and accurate repair of significant bone defects, enabling patients to safely bear weight and engage in functional exercises shortly after surgery. By establishing a multi-center clinical case cohort, the study aims to gather comprehensive data on the effectiveness of this innovative approach in treating various types of bone defects.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with traumatic, infected, or neoplastic lower limb bone defects greater than 5 cm.
Not a fit: Patients who cannot tolerate surgery or do not agree to the use of 3D printed prostheses may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery times and outcomes for patients with lower limb bone defects.
How similar studies have performed: While the use of 3D printing in medical applications is gaining traction, this specific approach to lower limb bone defect repair is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with traumatic lower limb bone defect; 2. Infected lower limb bone defect patients; 3. Patients with neoplastic lower limb bone defect; 4. The above reasons caused bone defects of more than 5CM 5. at least 18 years of age; 6. Sign an informed agreement and join the study cohort voluntarily. Exclusion Criteria: 1. Patients who do not agree to the use of 3D printed microporous titanium alloy prostheses; 2. Patients who cannot tolerate surgery; 3. the subjects cannot comply with the follow-up or affect the scientific and integrity of the study; 4. Other patients who were not suitable for inclusion as assessed by clinicians.
Where this trial is running
Beijing, Haidian
- Peking University Third Hospital — Beijing, Haidian, China (RECRUITING)
Study contacts
- Study coordinator: Bingchuan Liu, Doctor
- Email: liubc@bjmu.edu.cn
- Phone: +86 18310188678
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Bone Defects, 3D printing technology, bone defects, clinical effects