Uretheroileal suspension technique during radical cystectomy
Official title: Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy and Ileal Neobladder: A Prospective Randomized Comparative Study
Run by Sohag University · NCT06783855 · Data updated 2026-11-12
This study is testing a new surgical technique during bladder cancer surgery to see if it helps patients recover better than the usual methods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | January 22, 2025 |
| Trial ID | NCT06783855 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with muscle-invasive bladder carcinoma or specific cases of non-muscle-invasive bladder carcinoma that are unresponsive to other treatments.
✕Probably not a fit
Patients with benign bladder conditions, severe renal dysfunction, or poor overall health status may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the outcomes of a uretheroileal suspension technique used during open radical cystectomy for patients with muscle-invasive and certain non-muscle-invasive bladder cancers. The procedure involves ligating and dividing the puboprostatic ligaments and dorsal vein complex, followed by the reconstruction of an ileal pouch. The study aims to assess the effectiveness of this technique compared to conventional methods in terms of surgical outcomes and recovery. Participants will undergo a detailed surgical process that includes specific suturing techniques to ensure proper anastomosis.
Why it matters
Potential benefit: If successful, this technique could improve surgical outcomes and recovery for patients undergoing radical cystectomy.
How similar studies have gone: While this approach is innovative, similar surgical techniques have shown promise in improving outcomes in bladder cancer surgeries.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient age \>18 years. * Muscle-invasive bladder carcinoma (MIBC). * Non-muscle-invasive bladder carcinoma (NMIBC) fulfilling the following criteria: 1. \- (recurrent disease that is unresponsive to other treatments 2. \- high-grade tumors (T1, carcinoma in situ) refractory to intravesical therapy 3. -Multifocal or recurrent high-grade tumors despite intravesical therapy and the tumor progression from NMIBC to MIBC). Exclusion Criteria: * NMIBC or benign disease. * Severe hepatic renal dysfunction. * Urethral involvement with bladder carcinoma. * Poor overall health status. * Severe renal dysfunction.
Where it's running
-
Sohag University Hospital
Sohag, Egypt Recruiting
Study contacts
- Study coordinator: abdelrahman m abdellah, assistant lecturer
- Email: abdelrahman.ahmed1@med.shag.edu.eg
- Phone: +201014649841
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Observing quality of life in patients after bladder cancer surgery
This study looks at how bladder cancer surgery affects the quality of life for patients over about 10 years by checking in with them each year.
-
Trauma registry at Sohag University Hospital
This study tests the creation of a trauma registry in the emergency department to collect data on injured adults admitted with polytrauma at Sohag University Hospital.
-
Prevalence of Myocardial Bridging and its relation to Coronary Plaques on MDCT
This study tests how common myocardial bridging is and whether it relates to coronary plaque in patients undergoing coronary CT angiography.
-
Septoplasty: see if it changes headache symptoms
This study tests whether septoplasty can change headache severity in adults with septal deviation and headache.
-
Predicting SLE Flares with Patient Reports and Machine Learning
Aims to test a low-cost, patient-reported outcome–based machine learning tool to see if it can detect lupus flares early and support care, especially in settings with limited resources.
-
Is geographic mismatch linked to short-term major heart problems after long drug-eluting stent placement?
This study checks whether geographic mismatch can predict short-term major adverse cardiovascular events after a long drug-eluting stent is placed in the coronary arteries.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.