Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Uretheroileal suspension technique during radical cystectomy

Official title: Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy and Ileal Neobladder: A Prospective Randomized Comparative Study

Run by Sohag University · NCT06783855 · Data updated 2026-11-12

This study is testing a new surgical technique during bladder cancer surgery to see if it helps patients recover better than the usual methods.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment60 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag)
StatusRecruiting
StartedJanuary 1, 2025
Main results expectedJanuary 1, 2026
Study endsJanuary 1, 2027
Registry record updatedJanuary 22, 2025
Trial IDNCT06783855 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 with muscle-invasive bladder carcinoma or specific cases of non-muscle-invasive bladder carcinoma that are unresponsive to other treatments.

Probably not a fit

Patients with benign bladder conditions, severe renal dysfunction, or poor overall health status may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the outcomes of a uretheroileal suspension technique used during open radical cystectomy for patients with muscle-invasive and certain non-muscle-invasive bladder cancers. The procedure involves ligating and dividing the puboprostatic ligaments and dorsal vein complex, followed by the reconstruction of an ileal pouch. The study aims to assess the effectiveness of this technique compared to conventional methods in terms of surgical outcomes and recovery. Participants will undergo a detailed surgical process that includes specific suturing techniques to ensure proper anastomosis.

Why it matters

Potential benefit: If successful, this technique could improve surgical outcomes and recovery for patients undergoing radical cystectomy.

How similar studies have gone: While this approach is innovative, similar surgical techniques have shown promise in improving outcomes in bladder cancer surgeries.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient age \>18 years.
* Muscle-invasive bladder carcinoma (MIBC).
* Non-muscle-invasive bladder carcinoma (NMIBC) fulfilling the following criteria:

  1. \- (recurrent disease that is unresponsive to other treatments
  2. \- high-grade tumors (T1, carcinoma in situ) refractory to intravesical therapy
  3. -Multifocal or recurrent high-grade tumors despite intravesical therapy and the tumor progression from NMIBC to MIBC).

Exclusion Criteria:

* NMIBC or benign disease.
* Severe hepatic renal dysfunction.
* Urethral involvement with bladder carcinoma.
* Poor overall health status.
* Severe renal dysfunction.

Where it's running

  • Sohag University Hospital
    Sohag, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.